[Facial nerve neuropathy (review of the literature)].
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Biomedical subjects
Publications and source records attributed to M I Rushanov.
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Cluster headache is a disputable and ill-defined problem of current neurology. The authors review data available on etiology, mechanisms of pathogenesis and therapy with special emphasis on biochemical and immunological disturbances; discuss nosology of the disease in the light of newly obtained evidence on its immunological aspects. An overall table of clinically justified treatments is presented.
Serotonin levels in patients with trigeminal neuralgia were studied according to the pain syndrome. The results evidence normalization of the blood serotonin concentration, possibly due to a favourable effect of therapy on serotonin metabolism, which reflects activation and optimization of the gate system for pain control.
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Blood plasma beta-endorphin concentrations were measured in 87 patients with various facial and head pain syndromes: trigeminal neuralgia or neuropathy Horner syndrome and migraine, facial autonomic pains. beta-endorphin concentrations were measured before and after treatment. In the groups under investigation, the neuropeptide showed opposite changes in plasma levels after the therapy depending on the type of the syndrome.
The levels of E-type prostaglandins were measured in patients with facial and headaches. The data on the prostaglandin levels suggest that the severity of pain syndrome should be taken into consideration in relieving the pain, and then the nosology should be considered. The use of drugs influencing the prostaglandin turnover in treating patients with facial and headaches is discussed.