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Biomedical subjects

M I Moldavskiĭ

Publications and source records attributed to M I Moldavskiĭ.

18 recordsLinked to original sources
PubMed1982

[Ovarian thecoma with amyloidosis].

A case of diagnosis of a variety of ovarian thecoma, a thecoma with amyloidosis of the stroma, in a patient with fibromyoma of the uterus is described. Brief clinical data, characteristics of the tumor morphology including polarization microscopy and histochemistry, and differential diagnosis of forms of amyloidosis are presented. The presence of amyloid in the thecoma is considered to reflect the capacity of the tumor theca-cells of mesenchymal origin to produce amyloid.

Amyloidosis↗
PubMed1982

[Phylogenetic aspect of human pathology].

In human diseases, the appearing signs of organisms more or less remote from man phylogenetically are usually considered to be atavisms which do not reflect the thesis of similarities in the evolutionary process. Phylogenetic similarities in human pathology represent recapitulations, parallelisms, and convergences. Since recapitulation was dealt with one of the previously published articles, this paper analyses parallelisms and convergences in pathology. By the examples of uterus malformations, gene and chromosome mutations, tumors, and tuberculosis it is shown that parallel development of a pathological sign consists in repetition in man of a species sign of an animal, in the emergence of phenotypically and genotypically homologous hereditary diseases, and in similar manifestations of modification changes of cells and tissues of man and other mammals. Convergent similarities even under pathological conditions develop in unrelated organisms. The subdivision of similarities existing in diseases into recapitulations, parallelisms, and convergences requires that the data of comparative anatomy and physiology, embryology and paleontology be taken into consideration.

Animals↗
PubMedDate not supplied

[Immunopathomorphology of the human placental barrier in the first trimester of pregnancy complicated by the inflammation of the birth-ways].

The effect of ascending infection of birth-ways on transport of maternal immunoglobulins (Igs) through the placental barrier in humans during the first trimester of pregnancy was studied. The transport of Igs is seen already in 3.5-to 5-week-old embryos, and different cellular and biochemical compounds participate at each stage of this process. Transport of Igs through the trophoblast is carried out due to the secretory component (SC) and, perhaps, to some other receptors. Monocytes together with Igs penetrate into capillaries between the endothelial cells and are transported with the blood all over the body. It seems that SC and other receptors help Igs to penetrate into capillaries through the endothelium. Further, Igs are transported with erythroblasts. In the development without infection the transport of IgG was seen in all cases studied. Inflammation of the birth-ways is accompanied by an increase in transport of all Igs, already in early embryogenesis. Three groups were distinguished: 1) abortions without inflammation; 2) cases with signs of moderate inflammation (endometritis, deciduitis); 3) cases with intensive inflammation with necrosis and leucocytic infiltration. Transport of Igs was seen in 77.8% cases of the first group and in all cases of groups 2 and 3. Transport of IgM was not found in the first group, but was seen in 50% cases of group 2 and 66.7% of group 3.

Biological Transport↗