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Biomedical subjects

M I Ferrer

Publications and source records attributed to M I Ferrer.

At least 19 recordsLinked to original sources
PubMed2005

Scientific management of Mediterranean coastal zone: a hybrid ocean forecasting system for oil spill and search and rescue operations.

The oil spill from Prestige tanker showed the importance of scientifically based protocols to minimize the impacts on the environment. In this work, we describe a new forecasting system to predict oil spill trajectories and their potential impacts on the coastal zone. The system is formed of three main interconnected modules that address different capabilities: (1) an operational circulation sub-system that includes nested models at different scales, data collection with near-real time assimilation, new tools for initialization or assimilation based on genetic algorithms and feature-oriented strategic sampling; (2) an oil spill coastal sub-system that allows simulation of the trajectories and fate of spilled oil together with evaluation of coastal zone vulnerability using environmental sensitivity indexes; (3) a risk management sub-system for decision support based on GIS technology. The system is applied to the Mediterranean Sea where surface currents are highly variable in space and time, and interactions between local, sub-basin and basin scale increase the non-linear interactions effects which need to be adequately resolved at each one of the intervening scales. Besides the Mediterranean Sea is a complex reduced scale ocean representing a real scientific and technological challenge for operational oceanography and particularly for oil spill response and search and rescue operations.

Disaster Planning↗
PubMed1994

Presence of X-AG carrier in frog (Rana esculenta) red blood cells.

Evidence is presented that the high levels of internal L-glutamic and L-aspartic acid in frog (Rana esculenta) red blood cells are due to the existence of a specific carrier for acidic amino acids of high affinity (Km = 3 microM) and low capacity (Vmax 0.4 mumol L-Glu.Kg-1 dry cell mass.10 min-1). It is Na+ dependent and the incorporation of L-glutamic acid can be inhibited by L- and D-aspartate and L-cysteic acid, while D-glutamic does not inhibit. Moreover, this glutamic uptake shows a bell-shaped dependence on the external pH. All these properties show that this carrier belongs to the system X-AG family. Besides the incorporation through this system, L-glutamic acid is also taken up through the ASC system, although, under physiological conditions, this transport is far less important, since it has relatively low affinity (Km 39 microM) but high capacity (Vmax 1.8 mumol L-Glu.Kg-1 dry cell mass.10 min-1).

Amino Acid Transport System X-AG↗
PubMed1983

The influence of editing on the performance of a computer program for serial comparison of electrocardiograms.

In this study, three tests of computer ECG analysis function were conducted: 1) interpretation of serial tracings using the single record analysis program, i.e. without serial comparisons; 2) interpretation of the same tracings using a computer-comparison program; and 3) interpretation of these tracings using not only a computer-comparison program but also an editing program which allows amending of each serial record and insertion of any corrections into the computer data base before the next comparison. There was an over-all reduction of 84% in the number of statement changes needed to produce a correct final report by using the combined comparison and editing program. When this combined program was used, 81% of all computer interpretations required no alteration, --a considerable saving of time in analyzing serial electrocardiographic tracings. Serial comparison was required in in 27--45% of all ECG's taken in four medical centers.

Arrhythmias, Cardiac↗
PubMed1982

The etiology and natural history of sinus node disorders.

Two aspects of sinus node disorders currently seem to need emphasis--the etiology, which is still a difficult area, and the detailed structuring of the natural history of the sick sinus syndrome (SSS). The latter is becoming much clearer. The multifaceted influences of normal S-A nodal functions are reviewed. Degenerative fibrosis is the commonest abnormality, and coronary artery disease is not a major cause of the syndrome. The framework of the progressive natural history of the SSS in its usual sequential phases can now be constructed. Of course, not every feature of this progression is perceived in each patient. Gradually developing stages are reviewed, new data concerning behavior of rescue rhythms in S-A node disorders are presented, and a brief comment concerning the needs for and complications of pacing is included.

Atrial Fibrillation↗
PubMed1980

Sports hazards.

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Athletic Injuries↗