Search PubMed⌕ Search

Biomedical subjects

M Hubbard

Publications and source records attributed to M Hubbard.

59 records · Page 4Linked to original sources
PubMed1974

Hemoglobin Grady: the first example of a variant with elongated chains due to an insertion of residues.

A black 25-year-old woman and her father have a fast-moving alpha chain variant in an amount of 8% (the father) and 18% (the daughter). Structural data indicate that this chain has been elongated by the addition of three amino-acid residues to give the sequence: -Pro(114)-Ala(115)-Glu(116)-Phe(117)-Thr(118)-Glu-Phe-Thr-Pro(119)-Ala(120)-. The underlying genetic alteration responsible for hemoglobin Grady appears, therefore, to be a tandem duplication of nine base pairs which may have arisen by a process of mismatched intragenic crossing over. Functional and physicochemical properties of the variant are not greatly altered, and hematological data are normal.

Adult↗
PubMedDate not supplied

Anterior shoulder dislocation. A simple and rapid method for reduction.

Anterior shoulder dislocation is a common skiing injury. Several methods are available for reduction of shoulder dislocations. We evaluated a method for reduction of anterior shoulder dislocation that has not previously appeared in the literature. This method is performed with the patient seated in a chair with the chair used as countertraction. The physician applies traction to the affected shoulder using downward pressure on a loop of stockinette wrapped around the patient's forearm. Our method was successful in 97% of 118 anterior dislocations with no complications. Ninety-three percent were performed without the use of narcotic analgesia.

Adolescent↗