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Biomedical subjects

M Hoyos

Publications and source records attributed to M Hoyos.

26 records · Page 2Linked to original sources
PubMed1988

Diagnosis of malignant ascites. Comparison of ascitic fibronectin, cholesterol, and serum-ascites albumin difference.

The ascitic fluid concentrations of cholesterol and fibronectin and the serum-ascites albumin difference were compared with two conventional tests of ascitic fluid, total protein and LDH, in their diagnostic ability for detection of malignancy in ascitic samples from 69 patients with ascites: 54 with ascites due to liver disease and 15 whose ascites was caused by peritoneal metastases. Sixteen cirrhotic patients with superimposed hepatocellular carcinoma in whom ascites was of uncertain etiology were considered separately. The mean ascitic fluid total protein, LDH, cholesterol, and fibronectin values in the peritoneal metastases group were 3.70 +/- 1.20 g/dl, 247.26 +/- 148.14 units/liter, 109.06 +/- 29.85 mg/dl, and 91.57 +/- 41.52 micrograms/ml, respectively, and all were significantly higher than the corresponding values in the liver disease group (P less than 0.001), which were 1.37 +/- 0.59 g/dl, 75.40 +/- 110.70 units/liter, 23.75 +/- 11.22 mg/dl, and 31.86 +/- 10.51 micrograms/ml, respectively. Mean serum-ascites albumin difference in the peritoneal metastases group was 0.62 +/- 0.38 g/dl, which was significantly different from the corresponding value in the liver disease group (1.92 +/- 0.41 g/dl, P less than 0.001). Both ascitic cholesterol above 46 mg/dl and an ascitic fibronectin concentration greater than 50 micrograms/ml had high diagnostic accuracy (97%) for malignancy, being higher than that achieved using a serum-ascites albumin difference under 1.1 g/dl and an ascitic total protein above 2.5 g/dl, which had accuracies of 94% and 93%, respectively. Ascitic fluid LDH was the least reliable test. No differences in the ascitic fluid analysis were found between cirrhotic patients with and without hepatocellular carcinoma.(ABSTRACT TRUNCATED AT 250 WORDS)

Ascites↗
PubMed1983

Filariasis in Colombia: prevalence and distribution of Mansonella ozzardi and Mansonella (=Dipetalonema) perstans infections in the Comisaría del Guainía.

A survey was conducted to determine the prevalence and distribution of filarial infections among the inhabitants of Comisaría. Approximately 25% of the 604 individuals bled (Knott's sample) harbored microfilariae; more men (29.7%) were infected than women (23.7%); approximately 6% were infected with Mansonella (=Dipetalonema) perstans, 13% with Mansonella ozzardi, and 7% with both filariae. Mansonella ozzardi was more common in men than in women, and its prevalence increased with age in both sex groups; it was detected in most of the resident ethnic groups but was most common in the Puinave and the Curripaco Indians, and appeared to be distributed throughout the Comisaría. The prevalence of M. perstans was essentially the same in men as in women, and in age-groups from the 2nd to 4th decade, although its tendency to increase with age was not as marked as in M. ozzardi infections. Mansonella perstans appeared to be limited to the central and southern regions of the Comisaría, was found principally in the Curripaco Indians, and was detected in settlements situated within the drainage of both the Río Orinoco and the upper Río Negro. Approximately 9% of the white settlers (colonos) harbored M. ozzardi, and 5% M. perstans. These results indicate that both M. perstans and M. ozzardi are endemic in the Comisaría del Guainía, and suggest that the focus of M. perstans may extend further into the South American continent along the Río Negro and its tributaries.

Adolescent↗
PubMed1982

Filariasis in Colombia: presence of Dipetalonema perstans in the Comisaría del Guainía.

Examination of 75 blood samples (Knott preparation) collected in Puerto Inŕida, Coco, and Pajuil, in the Comisaría del Guainía, Colombia, disclosed 26 microfilaria carriers. Eighteen persons harbored only Mansonella ozzardi microfilariae, three were infected with M. ozzardi and Dipetalonema perstans and five harbored only D. perstans. M. ozzardi infections were found in whites, and in Indians belonging to the Curripaco, Puinave, Tukano, Guanano and Saliva tribes, but D. perstans was found only in the Curripaco Indians. Numbers of circulating microfilariae (mf) were low, 73% of the carriers had less than 200 mf/ml of blood: persons who harbored only D. perstans had less than 310 mf/ml. These results confirm the presence of D. perstans in Colombia, and suggest that its prevalence and distribution in the Comisarïa del Guainía and neighboring areas may be far greater than has been hitherto suspected.

Adolescent↗
PubMedDate not supplied

Portal vein absence and nodular regenerative hyperplasia of the liver with giant inferior mesenteric vein.

We present a patient with nodular regenerative hyperplasia of the liver (NRH) and portal vein absence studied with CT, MR imaging, and MR angiography. The most striking feature was exuberant hemorrhoids due to a giant hepatofugal inferior mesenteric vein. A relationship between unbalanced portal blood flow and nodular regenerative transformation of the liver is suggested in this patient.

Adolescent↗