Biomedical subjects

M Hovorková

Publications and source records attributed to M Hovorková.

3 recordsLinked to original sources

PubMed2004

[Selective laser trabeculoplasty].

The prospective clinical study of the selective laser trabeculoplasty (SLT) by means the Coherent Selecta 7000 laser (wave length 532 nm) was conducted. Totally 108.7 +/- 18.3 laser non-overlapping spots (mean energy level 1.04 +/- 0.22 mJ) along the whole circle of the trabecular meshwork in the anterior chamber angle were applied. The study included 258 eyes of 146 patients (50 of them were men) with glaucoma. The mean age of the whole group was 55.9 +/- 13.7 years. The group of unsuccessfully treated patients (30 patients, 41 eyes) in whom the intraocular pressure (IOP) elevated from 23.2 +/- 3.7 mm Hg in 4.7% (measured 493 +/- 474 days after the treatment) during the follow up, was removed from the study. In the group with good response to the SLT, 116 patients (217 eyes) were evaluated 650 +/- 405 days after treatment. Before treatment, in this group the IOP was 23.9 +/- 3.0 mm Hg, at the end of the study the IOP was lowered by 4.5 +/- 2.9 mm Hg, in total by 18.6%. IOP decrease was more pronounced in patients with higher level of IOP at the beginning. Immediately after SLT, no significant rising of the IOP level was recorded. Selective laser trabeculoplasty preserves the integrity of the trabecular meshwork of the anterior chamber angle, and is a safe and clinically effective method of treatment of different forms of glaucoma and ocular hypertension.

Adolescent↗

PubMed2002

[Effect of YAG capsulotomy of secondary cataracts on visual functions].

1. 20 patients (20 eyes) with secondary cataract and best corrected visual acuity (BCVA) of 20/30 or 20/20 using Snellen charts were examined before Nd-YAG capsulotomy and 14 days postoperatively. 2. Contrast sensitivity (CS) was tested on a computerized system of the Contrast sensitivity 8010 type and on VCTS charts in 6 spatial frequencies, BCVA was measured on the logMAR charts with Landolt rings and influence of glare of 342.6 cd/m2 was tested using Brightness Acuity Tester (BAT). 3. BCVA (without and under glare) in patients before and after YAG capsulotomy was significantly lower compared to the control group (p < 0.001). Postoperative improvement of BCVA was markedly higher on logMAR charts (up to 6.6 standardized lines) than using Snellen charts (1 line). 4. CS (without and under glare) using both methods in patients before and after YAG capsulotomy was significantly lower compared to the control group (p < 0.05 to p < 0.001) in spite of significant improvement postoperatively (p < 0.05 to p < 0.001), first of all at intermediate and high spatial frequencies. 5. Glare had only nonsignificant influence on BCVA and CS in all groups.

Aged↗

PubMed2000

[Use of 5-fluorouracil in trabeculectomy].

The cytostatic 5-fluorouracil (5-FU) is used at present in the postoperative treatment of glaucoma. In 1993-6 we administered by the subconjunctival route at the Ophthalmological Clinic in Hradec Králové 5-FU to a group of 158 eyes after trabeculectomy (TE). The basic indication was ingrowth of the filtration vesicle or a rise of intraocular tension to 20 torr and more in 148 eyes. Preventively 5-FU was administered during operation during revisions of TE in 10 eyes. In the mentioned group with an unfavourable course of postoperative scar formation in the wound we achieved during the investigation period of two years after surgery normalization of the intraocular pressure to less than 16 torr without further treatment (we consider the value and condition without treatment as the optimal condition) in 37% of cases and in 81% less than 20 torr with treatment. Side-effects of administration of 5-FU (most frequently erosion of the corneal epithelium were transient. For the mentioned indications 5-FU appears, being a cytostatic where the dosage can be exact, sufficiently safe for administration and it exerts an optimal effect.

Adult↗