[Senile involution and atrophy of the spleen].
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Biomedical subjects
Publications and source records attributed to M Houcke.
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The authors describe the case of a 51 year-old woman presenting with a very large laryngeal paraganglioma in the aryepiglottic fold which had passed through the cricothyroid membrane and invaled the thyroid. A crico-hyoido-pexy enabled the tumour to by completely removed and anatomo-pathological examination showed degeneration. Under electron microscopy, the ultrastructure of the tumour was similar to that of chromaffin paragangliomas. It is three years since this patient was cured.
Because of its important and its soft consistency, the thyroid is not always convenient for punction. Many smears cannot be classified, others are disappointing. The analysis of 2,300 punctions of thyroid lesions, allowed the authors to realise 900 comparisons between histopathological and cytological results. Among 300 histological malignant lesions, 89 unknown cancers were found, 40 of which gave haemorragic smears. The real false diagnosis were especially linked to vesicular and papillary carcinomas. On the other hand, undifferentiated carcinomas and lymphomas usually led to a correct interpretation. A correct diagnosis was made in 70% of all smears and in 81% of interpretable smears. The best results are found in benign lesions. The interpretation is correct in 94% of 600 punctions. A false diagnosis of malignancy is made in 6.1% of cases. So, this method fails to recognize an important number of cancers. It is not sufficient to assert the diagnosis and must be followed by an histopathological per-operatoire study. On the other hand a cytological diagnosis of cancer is reliable as long as the cytologist is not impressed by some cellular changes which are not so significant, as far as thyroid lesions are concerned, as in other fields of cytology.