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Biomedical subjects

M Houcke

Publications and source records attributed to M Houcke.

At least 19 recordsLinked to original sources

[Corticoadrenal tumors in children. Apropos of 3 cases and review of the literature].

Report of corticoadrenaloma in three children (1 malignant and 2 benign tumors). These 3 cases are analysed in comparison with the 72 cases found in the medical literature. From the whole series, it can be concluded that these tumors are rare, and occur predominantly in females and in very young children. Clinically, the secreting forms with rich and variable symptomatology contrast with the tumoral forms usually asymptomatic. The diagnosis between benign and malignant tumors remains difficult in cytopathological studies. In benign form, the treatment is always surgical and is successful. In malignant form, surgical treatment must be completed by chemotherapy, but the prognosis is definitively better if the tumor could be entirely removed.

Adolescent

Villous adenomas of the rectum. Results of endoscopic treatment with argon and Nd:YAG lasers.

Endoscopic treatment of rectal villous adenomas with argon and neodymium:yttrium aluminum garnet lasers is reported in 56 patients. Patients treated include 25 who had polyp recurrence after non-laser polyp treatment, 8 who had small sessile polyps that would otherwise require major surgery, and 23 who had contraindications to surgery. Complete tumor ablation was documented over a 3-24-mo follow-up period in 42 of the 56 treated patients. Of the remaining 14 patients, 5 were referred for other therapy because invasive carcinoma developed during treatment, 5 could not be assessed with confidence because of radiation proctitis, and 4 were lost to follow-up. In all patients with symptoms, improvement was noted when 75% of the tumor was destroyed. Treatment was well tolerated with no major complications. The results compare favorably with conventional treatment. Because laser tissue destruction precludes complete histologic evaluation of polyp tissue, laser ablation of polyps should presently be limited to (a) patients with recurrent tumors after previous non-laser treatment who refuse surgery, (b) patients with serious contraindications to surgery, and (c) small benign tumors that would require major surgery.

Adenoma

Vascular anatomy of the pisiformis bone.

The authors examined 41 dried pisiform specimens; it was found that the vascular apertures were situated on the lateral aspect, in the proximal half of the ridge occupied by the ulnar artery, on the medial aspect and at the distal tip of the bone. An average number of 6.9 foramina were encountered, their mean diameter attained 40/100 mm. In 34 injected specimens the nutrient vessels of the pisiforme were traced from the ulnar artery and its carpal dorsal and deep volar branches; all the tiny bony twigs anastomosed with one another and contributed to an arterial circle running around the pisiforme. The carpal dorsal artery which provides at least 2 descending branches toward the proximal tip of the bone, can be called the main pedicle; when its superficial branches are ligated, the pedicle is long enough (3 cm) to make the replacement of the lunate by the pisiform attached to the flexor carpi ulnaris quite safe in Kienböck's disease, without any risk of osteonecrosis.

Arteries

[Gastric metastasis of a malignant melanoma of the choroid].

Gastric metastases of choroid malignant melanoma seem to be exceptional since less than 10 cases have been previously published. We report the case of a 71 year old patient with a gastric melanosarcoma secondary to a choroid malignant melanoma. Gastric metastasis was revealed by digestive bleeding occurring 18 years after right eye enucleation. Gastroscopy showed black ulcerated tumors. Histology confirmed the diagnosis portraying typical melanic pigments within the gastric mucosa. Laser photocoagulation of the gastric lesion was used for the first time in this indication. As a result, hemorrhage decreased and the patient's comfort was improved.

Aged

[Puncture biopsy in the diagnosis of papillary epitheliomas of the thyroid].

In this study of the cytological appearances of papillary adenocarcinoma of the thyroid after fine needle aspiration biopsy, the authors have brought together 60 examinations of thyroid nodules and 10 indicant ganglial metastases. They isolate three significant aspects. type I (25 cases) is notable for the dense cellular desquamation in papillary clusters with angular contours, numerous calcospherites and, above all, the presence of intranucleaur pseudo-inclusion bodies (PI) which are clearly visible after coloring with May Grunwald stain. Type II (17 cases) was mainly observed in cystic lesions (8 cases) and metastatic ganglia (6 cases). It shows thick clusters of necrotic cells, few PI, barely visible against a background preparation of lysated hemates, polynuclear cells and macrophages. Type III (19 cases) consists of layers of cells poor in cytonuclear anomalies. The presence of PI is both a prerequisite and sufficent arounds for a diagnosis of papillary carcinoma of the thyroid, which will always be confirmed by subsequent histopathological examinations. The absence of PI leads to a false negative result. Better knowledge of cytological aspects specific to papillary tumors of the thyroid improves the quality of the diagnosis, not in terms of the percentage of carcinomas identified, which rises from 75.6 to 77% at a second reading, but in the specification of the papillary type, which rises from 38.5 to 64.2%. In the absence of PI and cytonuclear anomalies, non-identification of the carcinoma (22.8%) results from uninterpretable smears (5.7%) and false negatives (17.1%). There were no false positives. Cytological examination after fine needle aspiration biopsy should be included in the preoperative examinations of all thyroid nodules, as well as in the exploration of cervical ganglia likely to host an indicant or delayed metastasis.

Biopsy, Needle

[Congenital fibromatosis. Anatomical and clinical study on three observations (author's transl)].

Three congenital fibromatosis are studied. Six years later, the subcutaneous and skeletal lesions of the first patient have disappeared with no recurrence. Regression was also observed in the second one, a generalized fibromatosis with skeletal, subcutaneous and almost certainly pulmonary and laryngeal lesions. The last case is now progressing (vertebral lesion) with a vascular invasion, the prognostic of which is unknown. A review is made about microscopical appearance, origin and difficulties in diagnosis.

Diagnosis, Differential