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Biomedical subjects

M Horowitz

Publications and source records attributed to M Horowitz.

At least 577 records · Page 32Linked to original sources
PubMed1976

Stress films, emotion, and cognitive response.

The clinical theory of the repetition compulsion is sometimes taken to mean that neurotic persons, when traumatized, will develop compulsive repetitions of the trauma. Our experiment suggests that there is a more general effect--that various types of persons, after a variety of stressful events, will tend to develop intrusive and stimulus-repetitive thought; the stress itself does not necessarily have to have a negative valence. Equivalent effects were noted after stimuli that aroused positive emotions and after those stimuli that aroused dysphoric affects.

Arousal↗
PubMed1976

Cell interaction in tumor allograft immunity. Suppressor cell in the spleen of allogeneic tumor-sensitized mice.

The cytotoxic activity of lymphoid cells from allogeneic tumor-sensitized mice in three different strain combinations was tested at various intervals after i.p. sensitization. Peritoneal cells (PC) gave the highest cytotoxic index. The cytotoxic activity of the PC was due to both peritoneal lymphocytees (PL) and peritoneal macrophages (PM). Splenic macrophages, on the other hand, exerted an inhibitory effect as evidenced by increased cytotoxic activity of spleen treated with antimacrophages serum (AMS). Increased cytotoxic activity was also found in: (1) the nonadherent fraction of spleen after absorption on glass; (2) the effluent fraction of spleen after nylon wool column filtration; and (3) the medium density band after centrifugation of spleen on a discontinuous bovine serum albumin gradient. The results suggest the presence of an AMS-sensitive, glass- and nylon wool-adherent spleen cell which could have a suppressor role in allogeneic tumor-sensitized mice.

Animals↗
PubMed1975

Determination of plasma volume by 113min-labeled transferrin.

The binding property of ionic indium (In3+) with plasma transferrin was utilized for determination of plasma volumes (PV) of whole body and individual organs in small animals. Plasma transferrin from a donor rat was labeled with 15-17 muCi 113mIn/ml plasma and injected into the tested rats. PV were determined either by extrapolation to the dilution at time zero (for whole animals) or by calculation of the ratio, organ radiation: radiation of a plasma unit volume (for organs). The reliability of the method for determination of whole-body PV was ascertained by comparing the results obtained with those obtained simultaneously by the Evans blue dilution method. Whole body PV values obtained by the two methods were similar, with a correlation coefficient (r) of 0.997. The short half life of 113mIn enables it to be used with other nuclides which have similar or different energies in the same sample; indium radiation was counted first and after it had disappeared the activity of the other nuclide could be measured.

Animals↗