Biomedical subjects

M Hildesheimer

Publications and source records attributed to M Hildesheimer.

9 recordsLinked to original sources

PubMed1992

[Cochlear implantation].

Since the Israeli cochlear implant program was started in June 1989, 74 candidates have been evaluated for implantation. The main causes for hearing loss were meningitis (16 patients), aminoglycoside toxicity (9), congenital (6), viral (e.g. mumps) (6), and middle ear infection. Candidates were rejected mainly due to psychosocial factors (40%) and audiological parameters (30%). 16 postlingual deaf were implanted. In 7 of them (43.7%) the results were excellent, in 4 (25.0%) good, in 3 (18.7%) fair; 1 case is currently in a training program and 1 is a failure. There were 2 major complications: facial nerve palsy which necessitated surgical decompression, and insertion of the electrodes into the hypotympanic air cells, corrected by reoperation.

Cochlear Implants↗

PubMed1992

Temporary threshold shift due to noise exposure in guinea pigs under emotional stress.

One of the factors which can affect the amount of temporary threshold shift (TTS) due to acoustic overstimulation is known to be the general metabolic state of the exposed subject. The present study was conducted to elucidate how preexisting intense emotional stress in awake guinea pigs could influence the TTS induced by exposure of 4 kHz at 120 dB SPL for 20 min. Considering the hypersympathetic activity in both 'stress' and 'noise' it was assumed that the two factors would act synergetically on the cochlear function. However, an unexpected result was obtained. The mean threshold for the stressed animals following noise exposure was significantly lower (better) than that of the controlled, sedated, guinea pigs.

Acoustic Stimulation↗

PubMed1992

Cooperation of hearing-impaired elderly subjects for participation in a hearing screening program.

Presbyacusis, the auditory disorder which accompanies the aging process, is well known. However, the practical assistance available to alleviate the breakdown in the communication ability of the older person is unsatisfactory, and provision for public awareness of a rehabilitation strategy has not yet been established in many countries. Four hundred and ninety-eight elderly subjects, aged 65-94 years, were hearing tested in different setups, a geriatric nursing home and in the community. It was found that the need for rehabilitation was high and the willingness to participate in a hearing screening program was low even though the rehabilitation treatment was provided without charge.

Age Factors↗

PubMed1991

The effect of bilateral sympathectomy on noise induced temporary threshold shift.

The cochlea is innervated by sympathetic nerves originating or passing the superior cervical ganglion. The termination of one type (the vascular independent) is in the habenular region close to the auditory nerve fibers, and the other, the perivascular type, is associated with blood vessels, particularly in the spiral vessel of the tympanic lip. Suggested functions have so far received partial evidence in the literature. Borg (1982) suggested the protective value of sympathectomy of the ear in noise. Our experiments further elaborate this protective value, as it was seen that bilateral cervical sympathectomy diminished the temporary threshold shift in awake, sound exposed GP.

Acoustic Stimulation↗

PubMed1991

Sedation effect on temporary threshold shift induced by acoustic overstimulation.

The mechanism by which noise damages the inner ear has not as yet been fully elucidated. Experiments were done to study the influence of the sedation in temporary threshold shift (TS) induced by acoustic overstimulation, as barbiturates were found to improve the brain's tolerance to ischemia. Four groups of guinea pigs (GP) were used. The temporary TS was decreased with the reduction of the temperature in awake, as well as sedated, sound-exposed GP. However, the temporary TS in the sedated, but normothermic GP was as great as in the awake, normothermic group. The high temperature counteracts the protection effect of the sedation in nose-induced hearing loss.

Acoustic Stimulation↗

PubMed1991

Central auditory skills in blind and sighted subjects.

Three different central auditory skills were compared and evaluated in 56 blind and 40 sighted subjects. The study consisted of three experiments conducted in three subgroups. Experiment A was performed in order to evaluate the localization function; experiment B for the temporal auditory resolution ability of the blind adult, and experiment C to test the ability of the blind person to discriminate speech material in noise. In all three experiments the blind subjects obtained significantly better results than the sighted subjects. From these results it was concluded that there is supporting evidence of a certain superiority of the blind individual with regard to central auditory function.

Adolescent↗

PubMed1979

Long-term electrode implantation for recording cochlear electrical activity in guinea pigs.

Comparative measurements of the cochlear electrical activity over prolonged periods require long-term implantation of electrodes. During this time, changes in the electrode recording ability and/or impairment of the sound-conducting system, could erroneously be attributed to the experiment. To avoid this risk, an easy and reliable technique is described. The procedure uses the Fallopian canal as a route by which to approach the cochlear potentials' generators, while leaving the middle ear untouched.

Action Potentials↗

PubMed1977

Chronic cardiovascular pathology and hearing loss in the aged.

With the objective of studying a possible correlation between chronic cardiovascular disturbances and hearing loss in aged people, two groups were compared. The first was composed of apparently healthy subjects and the second, of subjects suffering from clinically evident chronic cardiovascular pathology. All the subjects were submitted to a pure tone audiometry, discrimination test, SISI test and TDT. The results showed a significant difference in pure tone threshold audiometry between the apparently healthy subjects and those presenting cardiovascular symptoms; the discrimination and the TDT were comparable in the two groups.

Aged↗

PubMed1975

Cochlear action potentials in experimentally induced hypothyroidism in guinea pigs.

Hypothyroidism was induced in guinea pigs by various methods. Using a new technique, electrodes were permanently implanted and action potentials aroused by different sound stimuli recorded and measured. The results obtained before and during the hypometabolic state were analysed and compared with those obtained after replacement therapy. A tentative attempt was made to extrapolate the changes in pattern and magnitude of the action potentials caused by the experimentally induced hypothyroidism, to the hearing disorders observed in patients with thyroid deficiency.

Acoustic Stimulation↗