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Biomedical subjects

M Hida

Publications and source records attributed to M Hida.

At least 55 records · Page 3Linked to original sources

[Vitamin and mineral status in chronic renal failure--the effect of protein restriction].

Essential amino acid (EAA), vitamin and mineral abnormalities are found in patients with chronic renal failure (CRF). We considered altered dietary restriction to be one of many factors that can promote these abnormalities. We determined the EAA, vitamin and mineral content of low-protein diets and vitamins and minerals in the blood of outpatient populations with various degrees of CRF (serum creatinine 3.6-6.8mg/dl). The results obtained were as follows: 1. 20g-protein/day diet can provide an adequate amount of EAA. 2. Low protein diets (30g protein/day diets) were inadequate in vitamins A, B1, B2 and B6. Vitamins A, B1, B2 and B6 in these diets were 70-80%, 40-50%, 30-35% and 20-25% of the minimum daily requirements, respectively. 3. Low protein diets (30g protein/day diets) were inadequate in Ca, Fe and Zn. The Ca and Fe contents of these diets were 30% and 50% of the minimum daily requirements, respectively. The Zn content of a diet rich in vegetable protein, although low in protein, overall (vegetable: animal = 2:1), was about 55% of the minimum daily requirement. 4. About 21.4% of the CRF patients had low levels of plasma vitamins B1. About 28.6% and 33.3% of the CRF patients had low levels of plasma vitamins B2 and B6, respectively. Plasma folic acid levels were not inadequate in these patients. 5. About 28.6%, 50% and 35.7% of the CRF patients had low levels of plasma Ca, Fe and Zn, respectively. In conclusion, it seems that supplementation of vitamins B1, B2, B6, Ca, Fe and Zn should be considered for protein-restricted CRF patients.

Amino Acids, Essential↗

[Evaluation of renal graft function with radionuclide dynamic images--application of modified Rutland's analytical method].

An uptake coefficient (UC) is estimated with applying the method proposed by Rutland to the renal dynamic images with 99mTc-diethyltriamine pentaacetate (DTPA). UC estimated with this method is proportional to glomerular filtration rate in the original Rutland's method the cardiac and renal time-activity curves (TAC) were used for input and output functions, respectively. In this paper, our method of estimating an input and output function by applying factor analysis method to renal dynamic images and it's clinical application are presented. In 11 patients, U"s estimated by this modified method revealed good correlations between the UCs and CCr (r = 0.75), between UCs and effective renal plasma flow (r = 0.67), and inverse correlations between UCs and serum creatinine values (r = 0.65). The results showed that UC in this method can be a useful parameter for grafted renal function. This method is simple in technique and applicable for the evaluation of split renal function in renal transplant donors.

Creatinine↗

Plasma free catecholamine level during hemopurification in a case of pheochromocytoma.

To examine the alteration of the plasma free-catecholamine level during hemopurification in a patient with pheochromocytoma, the levels of plasma free-catecholamine and total catecholamine in the filtrate were monitored pre- and post-hemopurification. Approximately 100 micrograms of total catecholamine was removed by the hemopurification procedure though the high level of plasma-free catecholamine remained unaltered.

Adrenal Gland Neoplasms↗

Plasmapheresis in the Tokai University Medical Center, 1983-1989.

There were 634 instances of plasmapheresis performed on 152 patients in the Kidney Center, Tokai University Hospital, in the seven year period from Jan. 1983 to Dec. 1989. The average number of plasmapheresis treatments per patient was highest for those with neurological and dermatological disease (6.7), followed by liver disease (5.6), and drug intoxication (1.2). The major treatment modalities for the liver, collagen, drug intoxication, hematologic, neurologic and hyperlipidemic disorders were plasma exchange (PE) and double filter plasmapheresis (DFPP). Recently, however, the use of plasma perfusion (PP) and immunoadsorbent plasma perfusion (IPP) has been increasing because of their ability to selectively adsorb various pathologic macromolecules.

Collagen Diseases↗

[The relationships between the difficulty of goal attainment and interpersonal attraction].

The purpose of this study was to examine the effect of the goal attainment difficulty upon interpersonal attraction for the partner. Eighty female undergraduates participated the experiment. They were given tasks with one of four different goal attainment level (very easy, easy, difficult, and very difficult). Each subject solved it with partners of one of three ability levels (superior, similar, inferior to the subject). After the completion of the task, all subjects were requested to evaluate the three partners' instrumental and emotional attractiveness. The main results were as follows: (1) The subjects evaluated the more capable partner as more attractive on the instrumental attraction dimension. (2) The subjects in easy and difficult goal attainment conditions evaluated the superior partner as most attractive on the emotional attraction dimension. While the subjects in very easy and very difficult goal conditions evaluated the similar partner as most attractive on that dimension. These results were discussed in terms of the relationship between the reward value of interaction partner and the task environment.

Adult↗

[Renal failure in paroxysmal nocturnal hemoglobinuria].

UNLABELLED: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired hemolytic disorder characterized by a membrane abnormality of red cells, and characterized by two major clinical features of gross hemoglobinuria and diffuse venous thrombosis. In Japan, the present report records the first case of acute renal failure complicating PNH with treated by hemodialysis and was almost completely reversible. CASE: A 41 year-old woman was admitted for high fever (39.8 degrees C), dyspnea and clinical signs of a respiratory infection. She was started on Cefotax 1,000 mg 3 times daily. She subsequently developed acute renal failure and which treated by hemodialysis and was almost completely reversible. Following treatment of her renal failure, respiratory infection and anemia, she initially made good progress and was discharged.

Acute Kidney Injury↗

[A case of polycystic kidney with bilateral nephrectomy].

A 56-year-old woman in chronic hemodialysis had been suffering from uncontrollable fever for the past 7 months. Her original disease was diagnosed as familial polycystic kidney and three of her five brothers were found to have the same disease. Her chromosome was 46,XX,21P+ and laboratory examination revealed severe anemia, malnutrition, liver dysfunction, pyuria and candidiasis of urine. Abdominal echogram and CT scan revealed polycystic kidneys and multiple liver cysts. She was admitted to our hospital and was diagnosed as having pyelonephritis of the right kidney. As her condition was not improved by conservative therapy right nephrectomy was performed. One month later, spiking fever and left tenderness reappeared. Those symptoms could not be controlled by conservative therapy and left nephrectomy was performed again. Pathological examination on nephrectomized kidneys showed interstitial nephritis, hyaline degeneration and proliferative change of glomeruli, microabscess, colloid of tubules and calcification of parts of Henle's loops. Nephrectomy has been performed in 1.6 to 10.0% of polycystic kidneys due to references since 1952. Eight of the 22 polycystic kidneys (36.3%) seen at our hospital during the past 10 years have been removed.

Female↗

Autopsy findings in 68 fatal renal transplant recipients, collected from the annuals of pathological autopsy cases in Japan.

This report describes autopsy findings in 68 fatal renal transplant recipients, collected from the Annuals of Pathological Autopsy Cases in Japan, 1981-1985, published by the Japanese Pathological Society. Direct causes of death in renal transplant recipients were mainly infections, bleeding, rejection, and liver dysfunction. Infectious complications were present in forty-one autopsy patients (60.3%). Bronchitis and pneumonia were the most frequent, followed by general infections and peritonitis. Fungal infections were present in twelve cases (17.6%). Bleeding was present in thirty-three autopsy patients (48.5%). Gastrointestinal bleeding was the most frequent, followed by general bleeding, and brain and/or subarachinoid bleeding. Liver diseases were present in twenty-eight autopsy patients (41.2%).

Adolescent↗

[Study on changes in plasma platinum concentrations after administration of CDDP to maintenance hemodialysis patients].

Changes in plasma platinum concentration after administration of CDDP were studied in six patients on maintenance hemodialysis with malignancies. Plasma exchange was carried out on three patients for the purpose of plasmapheresis. A therapeutic dose of 51 mg/m2 of CDDP was administered to each patient without any severe adverse reactions. Plasma platinum concentration was measured by atomic absorption spectrophotometry, and the decay curve of the agent showed a biphasic pattern with an initial steep alpha phase and an ensuing mild beta phase in both hemodialysis patients and normal controls. As these patterns showed no renal excretion of CDDP, it was suggested that the uptake of CDDP into tissue was one of the main causes of the steep alpha phase. In patients given plasma exchange one or two hours after the beginning of CDDP administration, the reduction rates of plasma platinum were 74.7-61.7%, but the collection rate of the agent in the exchanged plasma was only 22.2-7.5%. These results indicated that the uptake of CDDP into tissue might occur rapidly within a few hours after CDDP administration.

Adult↗