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Biomedical subjects

M Herrmann

Publications and source records attributed to M Herrmann.

At least 289 records · Page 16Linked to original sources
PubMed1976

Regulation of the activities of the enzymes involved in the metabolism of steroid hormones in rat liver: the effect of administration of anterior hypophyseal hormones and gonadotrophin preparations to hypophysectomized rats.

A crude human hypophyseal extract (HE), as well as human growth hormone (GH), ovine prolactin (PRL) and commercial preparations of ACTH, TSH, pregnant mare's serum gonadotrophins (PMS) and chorionic gonadotrophin (CG) were tested for their ability to induce the activities of cytoplasmic 17 beta-hydroxysteroid dehydrogenase and microsomal delta 4-5alpha-hydrogenase and to repress the activities of microsomal 3alpha- and 3beta-hydroxysteroid dehydrogenases in the liver of hypophysectomized rats. The activity of 17beta-hydroxysteroid dehydrogenase was not affected by any of the administered hormones. For the other enzymes, only PRL was effective in causing changes in the activities; the repressive effect on 3alpha-hydroxysteroid dehydrogenase activity was highly significant (P less than 0.001). These results indicate that PRL is involved in the regulation of at least some of the enzyme activities of hepatic steroid hormone metabolism.

Adrenal Glands↗
PubMed1975

[Bacteriological examinations of bronchial secretion in children with non-specific bronchopulmonary disease (author's transl)].

One thousand specimens of bronchial secretion from children with non-specific respiratory diseases have been examined bacteriologically. In spite of the complex nature of acute and especially of chronic respiratory disease the role of bacterial infection should not be underestimated. Thirty per cent of the specimens were sterile. More than 20 per cent of the bacterial species isolated from bronchial secretion were pathogenic. Relatively frequent was the isolation of E. coli and of pathogenic staphylococci. Nearly 40 per cent of all isolated bacteria were alpha-haemolytic streptococci. The latter have been found more frequently in children with, than in children without bronchological alterations. The pathogenicity of alpha-haemolytic streptococci in the bronchial tree is discussed.

Adolescent↗