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Biomedical subjects

M Henry

Publications and source records attributed to M Henry.

At least 397 records · Page 22Linked to original sources

[Cholestatic jaundice complicating lipomatous pseudo-hypertrophy of the pancreas].

The authors describe a major pancreatic lipomatous infiltration, causing a "pseudo-hypertrophy" of the pancreas, in a 70-year-old man. This lesion was responsible of a hyperechogenic area at ultrasonography and of an empty pancreatic bed ("vanishing pancreas") at computed tomography, suggesting lipomatosis. This entity is a special modality of senescence of pancreatic tissue whose origin remains obscure. The progressive atrophy of the acinar lobules and the islets of Langerhans was finally responsible of a mild degree of malabsorption and of diabetes type II. The compression of the main bile duct by the enlarged lipomatous pancreas, demonstrated by percutaneous cholangiography, caused a cholestatic jaundice with abdominal pain, which was treated by a surgical derivation (hepatico-duodenostomy). This is the first description of a lipomatous pseudohypertrophy of the pancreas causing an obstruction of the common bile duct.

Aged↗

Adenoid cystic carcinoma of the uterine cervix. Cytologic features.

A case of primary cervical adenoid cystic carcinoma in a 75-year-old woman is reported. Two cervical smears taken at the time of initial presentation for vaginal spotting were negative; a third smear, taken a year later prior to laparotomy, was diagnosed as positive. The cytologic findings in the positive cervical smear are described and illustrated. The differential diagnosis of the cytologic findings is discussed, and the literature on this lesion is briefly reviewed. The results in this case and others suggest that the diagnosis of cervical adenoid cystic carcinoma in an asymptomatic patient may be missed by routine smear examination.

Aged↗

[Double-blind versus placebo comparison of single dose alpidem (50 mg or 75 mg) in a model of situational anxiety].

Alpidem (Ananxyl) is a new imidazopyridine anxiolytic. Two studies of single doses of alpidem (50 or 75 mg) versus placebo, involving 104 patients each, showed alpidem at these two doses to be effective in a human model for situational anxiety, which is the psychological state of patients awaiting cardiovascular examination or surgery. Clinical assessment showed no significant difference in safety between alpidem 50 mg and placebo. Conversely, at the dose of 75 mg, there was a higher incidence of drowsiness with alpidem than with placebo.

Adult↗

Prevention of recurrence of deep vein thrombosis in pregnant and post-partum women.

Deep Vein Thrombosis is a relatively common complication of pregnancy and the post partum period. Women who have once suffered a deep vein thrombosis have an increased risk of recurrence with or without the possibility of pulmonary embolism during future pregnancies. Each year in the Rotunda Hospital Dublin about twenty such patients are seen out of a total of 6,000 pregnant women. Prophylactic treatment with low dose subcutaneous self-administered heparin is the regimen used. Patients for the past three years are surveyed--in all cases except one the pregnancy and post partum period was uneventful. In one case a late post partum non-fatal pulmonary embolus occurred.

Adult↗