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Biomedical subjects

M Henderson

Publications and source records attributed to M Henderson.

177 records · Page 10Linked to original sources

Some determinants of attrition in prospective studies on aging.

Demographic measures, psychosocial variables, and objective and subjective measures of physical impairment were assessed in elderly men twice at intervals of 12 to 18 months. Canonical discriminant function analysis of the relationship between these predictor variables on the first testing and whether participants (a) returned for retesting, (b) did not return because of apparent disinterest, or (c) did not return because of illness or death, revealed two significant canonical variates. The first, characterized by decreased mental and physical capacity, discriminated between the deceased/ill group and the other two groups. The second was characterized by decreased social interaction and life satisfaction, and increased life events, and distinguished between the disinterested group and the other two groups. However, both groups that failed to return for retesting showed evidence of impaired physical health and a general disengagement from social and personal activities, compared to the retested group.

Adaptation, Psychological↗

Burkholderia pseudomallei traced to water treatment plant in Australia.

Burkholderia pseudomallei was isolated from environmental specimens 1 year after an outbreak of acute melioidosis in a remote coastal community in northwestern Australia. B. pseudomallei was isolated from a water storage tank and from spray formed in a pH-raising aerator unit. Pulsed-field gel electrophoresis confirmed the aerator and storage tank isolates were identical to the outbreak strain, WKo97.

Australia↗

Drug-drug interactions among residents in homes for the elderly: a pilot study.

This pilot study investigated epidemiologically the potential for clinically significant drug-drug interactions, a subclass of adverse drug responses, in two homes for the elderly. The agent (drugs), host (residents), and environment (rural and urban nursing homes) in the illness known as drug-drug interaction were studied. Drug profiles on 188 subjects were compiled and screened by computer. Of these, 100 (80 in the rural home and 20 in the urban home) had the potential for clinically significant drug-drug interactions. Laboratory diagnostic procedures essential to confirm the unintentional interaction of two or more drugs were beyond the scope of the study; therefore, physicians independently reviewed the records of 66 residents who could be interviewed, agreeing that 27 residents were potential drug-drug interactors. These subjects had twice as many drug products and three times as many pro re nata products prescribed for them as did subjects without the potential for drug-drug interaction. The possible cause of interaction found most frequently was digitalis combined with thiazide or furosemide. The results of this pilot study suggest several implications for practice within the research setting.

Aged↗

What nurses don't know about AIDS.

As nurses care for ever increasing numbers of AIDS patients, they will face increased challenges that will tax knowledge and skill levels. To make the appropriate assessments and decisions about care and educational needs of the patient, the nurse needs a complete knowledge base that includes information about the pathophysiology, physiologic needs of the patient, and the diagnostic tools related to the disease process.

Acquired Immunodeficiency Syndrome↗

Information nurses need about AIDS.

The practicing nurse in today's health care system will be caring for many AIDS-affected patients. To make appropriate care decisions and disseminate facts about the disease process to co-workers, patients, and the public, the nurse needs to be knowledgeable about more than just the prevention and transmission precautions. Nurses also need in-depth knowledge about the pathophysiology of the disease, diagnostic methods used to confirm the presence of AIDS and its opportunistic diseases, and nutritional implications for patients. With an understanding of the AIDS disease process, the nurse is in a position to be a key component on the health care team caring for AIDS-affected patients.

Acquired Immunodeficiency Syndrome↗

The symptomatic status of patients one year following revascularization by either coronary surgery or angioplasty.

This study consisted of a one year clinical follow-up of 81 patients who had coronary revascularization. In 32 patients, this was accomplished by bypass surgery and in 49, by percutaneous angioplasty. Prior to the procedure the two groups of patients were similar with regard to age, sex, antianginal medication and angina severity with 75% of the surgical patients and 65% of the angioplasty patients in CCS Angina Class III or IV. Although most of the surgical patients had multivessel disease and most of the angioplasty patients had single vessel disease, all had complete revascularization. At one year, 78% of the surgical patients and 84% of the angioplasty patients did not have angina and few patients in either group were taking medication. However, in the intervening year 39% of the angioplasty patients had had a second revascularization procedure, whereas, only 3% of the surgical patients required a second procedure. Extracardiac sequelae were more frequent in the surgical cohort. Therefore, at one year following complete revascularization, bypass surgery and angioplasty result in comparable symptomatic and functional improvement.

Adult↗