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Biomedical subjects

M Hayran

Publications and source records attributed to M Hayran.

59 records · Page 4Linked to original sources

[New human polyomavirus; BK virus antibody levels in different age groups using the hemagglutination inhibition test].

In this study, 1123 human sera samples obtained from healthy persons belonging to various age groups were tested in order to detect the distribution of antibody levels against the new human polyomavirus, BK. All sera samples were tested by hemagglutination inhibition (HI) test and 881 (78.5%) of those were found to be positive and 242 (21.5%) were negative. The percentage of positivity was 65.3% between the ages of 1 to 5 years, and over 80% in the group aged 6 years or older. Furthermore, between 1 to 10 years of ages HI antibody titers were higher than the older age groups. Our results indicate that antibody to BK virus infections are remarkably frequent in our population and acquisition of BK virus appeared to be common in childhood.

Adolescent↗

[New human polyomavirus: comparison of hemagglutination inhibition, ELISA and complement fixation tests for BK virus serology].

In this study, 110 sera samples taken from healthy persons were tested for BK virus antibodies by using hemagglutination inhibition (HI), ELISA and complement fixation (CF) tests to detect the sensitivity, specificity and agreement of these tests. The results of each individual test was compared with others for sensitivity and specificity. Specificity found to be 96% when HI and CF tests were compared. Sensitivity also found to be 92.7% when CF and ELISA tests were compared. Agreement of HI and ELISA tests were 88%.

Antibodies, Viral↗

[The in vitro activity of ciprofloxacin against clinically-isolated strains of Pseudomonas aeruginosa and comparison with some other antibiotics].

In this study the susceptibility to ciprofloxacin of 100 Pseudomonas aeruginosa strains isolated from various clinical specimens was investigated by disk diffusion test and macrodilution method, and was compared with other various antibiotics. Both of the methods showed that 98 of the strains were susceptible to ciprofloxacin. MIC50 of ciprofloxacin was found to be 0.12, and MIC90 0.50 mcgr/ml for these strains. Pseudomonas aeruginosa strains were found to be highly susceptible to ciprofloxacin in in-vitro conditions.

Amikacin↗

[Human B-lymphotropic virus (HBLV): human herpesvirus-6 (HHV-6)].

Human B-lymphotropic virus (HBLV) is also known as human herpes virus-6 (HHV-6) and was isolated from patients with various lymphoproliferative disorders. In this article the biological, immunological and molecular properties of a new human herpes virus-6 is reviewed. The association of the virus with chronical disorders is also discussed.

Herpesviridae Infections↗

[A new rapid antibiotic susceptibility test for enteric bacteria using a color change method].

The rapid antibiotic susceptibility tests that have been developed so far cannot be used in daily work, because of their many difficulties and disadvantages. We have developed a new antibiotic susceptibility test for enteric bacteria which gives the result in 4 hours, easy to perform and inexpensive. This method depends upon the mechanism which detects the acid formed by the bacteria, by the change of the color of the pH indicator in the medium. The susceptibility of 110 different isolates of enteric bacteria (E. coli, Klebsiella, Salmonella, Shigella, Proteus, Enterobacter) to ampicillin, amikacin, trimethoprim-sulfamethoxazole, cephradine, cefazolin, erythromycin, gentamicin, and ofloxacin is examined by this new "Rapid Color Change Test" and disc diffusion method. For most organisms tested, there was a good correlation between the results of the two methods. The overall agreement is found to be 91.43%.

Anti-Bacterial Agents↗