Synthesis and processing of avian sarcoma virus glycoproteins.
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Biomedical subjects
Publications and source records attributed to M Hayman.
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ADVERSE INFLUENCES ON MOTIVATION FOR RECOVERY FROM ALCOHOLISM MUST BE SEARCHED FOR IN THREE AREAS: society, the medical practitioner and the patient. Society is ambivalent because there is a vicarious release through identification with the cheerful "drunk" coupled with unconscious envy and resentment leading to punitive action. The current "alcohol culture" decrees that to drink is to be well, not to drink is to be ill. The medical profession attempts to suppress, deny, rationalize or reject the problem of alcoholism because it involves a change in attitude and recognition of limitations. The alcoholic patient has a notorious lack of motivation, but this must be recognized as a symptom of his disease, and with certain techniques this symptom is treatable. Furthermore, motivation fluctuates and many opportunities for treatment are available when the medical practitioner can detect that motivation is high. At times a coercive approach is required, at times a permissive one; and the optimal use of such approaches will increase the motivation to an effective level.
Although the philosophy of the community mental health center has been applied to alcoholism since the early part of this decade, it has been pursued much more intensively in recent years, and there has been a decentralization in the management of alcoholics in a series of stages from the jail or work-house to the state hospital and to the clinic and the community. The medical practitioner now has opportunity to treat the alcoholic in private practice. Advances have been made in two directions. Advances in medical management have included reinforcement of the importance of hydration and electrolyte balance, particularly magnesium. Psychopharmacology has contributed three drugs particularly important in the management of acute alcoholism and its complications. These drugs are chlordiazepoxide, chlorpromazine, and thioridazine. Another drug, Antabuse, when properly used, has proven extremely valuable as a deterrent. Equally important have been administrative advances. The importance of the environment and its manipulation has been recognized, and a series of institutional and non-institutional resources, such as clinics, half-way houses, foster homes, and Alcoholics Anonymous has made it less likely that a patient will be turned away without help.
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Fifty septic knees in patients younger than 2 years old at diagnosis were examined. Follow-up ranged from 1.1 to 21.3 years (average, 6.2). Twenty-four knees were deformed in varus or valgus of 5-40 degrees. Deformity was present within 10 months of infection and thereafter was stable. It was due to displacement of the epiphysis into a metaphyseal defect, loss of epiphyseal cartilage, or both. Growth did not compensate for deformity. Ossific nuclei partly or completely disappeared after infection. They were slow to reappear, and until maturity, their size and shape did not represent the cartilaginous epiphysis. Arthrograms were necessary to evaluate accurately the epiphyseal shape and volume.
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Forty-six septic shoulders in 42 patients < 18 months old at diagnosis were followed for an average of 6 +/- 10 years. Eight were not diagnosed at the time of infection. Five patients complained of intermittent, mild pain with use. All could touch their mouth and back of their head with the hand on their affected side. Flexion and abduction averaged 150 degrees; internal and external rotation averaged 60 degrees. Nineteen percent of the shoulders had < 130 degrees of flexion. Discrepancy in humeral length was 0-9 cm (average 2.4 cm). Only 7% of the humeral heads were entirely normal. The shapes of the remainder were quite variable, and range of motion could not be predicted from these shapes.
The Patient's Charter states that people have the right to discuss and help to decide their care and treatment and that those with special needs are entitled to help when dealing with the NHS, including having someone to speak for them when necessary. This paper details the development of a protocol outlining the needs of people with hearing impairments with a view to ensuring staff have access to relevant specialist educational and communication skills.