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Biomedical subjects

M Harris

Publications and source records attributed to M Harris.

At least 703 records · Page 39Linked to original sources
PubMed1974

Phenytoin inhibition of parathyroid hormone induced bone resorption in vitro.

1 A study is reported of the effects of phenytoin and phenobarbitone on bone calcium mobilization by parathyroid hormone in vitro.2 In a therapeutic concentration (15 mug/ml), phenytoin significantly inhibited parathyroid hormone-induced calcium release from bone.3 The inhibitory effect of phenytoin on bone calcium mobilization could play a role in the maintenance of hypocalcaemia in epileptic patients on long-term anticonvulsant drug therapy.

Animals↗
PubMed1974

Nodular, non-cirrhotic liver associated with portal hypertension in a patient with rheumatoid arthritis.

A patient with rheumatoid arthritis developed portal hypertension and died from bleeding oesophageal varices. The liver was small and showed a nodular, non-cirrhotic pattern similar to that described by Blendis et al (1970 and 1974) in association with Felty's syndrome. This appears to be the first report of a patient with this liver lesion associated with rheumatoid arthritis in the absence of Felty's syndrome. The liver lesions described here are compared with partial nodular transformation and nodular regenerative hyperplasia; in spite of some differences it is not proven that these are distinct entities and further study is required to settle this question.

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