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Biomedical subjects

M Harell

Publications and source records attributed to M Harell.

30 records · Page 2Linked to original sources
PubMed1982

Toxic shock syndrome: otolaryngologic presentations.

Toxic shock syndrome is a recently discovered and widely publicized disease found to occur in young menstruating women and thought to be associated with the use of vaginal tampons. To this date, there has been no known report of a similar disease being caused by nasal or sinus packing. The following is a discussion of the toxic shock syndrome (TSS) and a presentation of two cases that demonstrated a striking similarity to that disease.

Adult↗
PubMed1978

Management of tinnitus aurium with lidocaine and carbamazepine.

At present there are two methods of management of tinnitus: one old, by masking with a noise generator, and one new, by biofeedback. Neither of these methods is convenient and neither gets at the heart of the problem. A third method, using intravenous lidocaine as a test and oral carbamazepine therapy, was developed in the Pain Clinic of the Auckland General Hospital in New Zealand. This paper will report our brief experience with these drugs in the management of tinnitus and other similar disorders. Twenty-seven patients with intractable tinnitus had a significant reduction from a test dose of intravenous lidocaine and were treated with oral carbamazepine. Of this group 1 patient (4%) had complete relief, 21 patients (78%) had partial relief, and 5 patients (18%) had no relief. Complications were few and not serious, and either disappeared spontaneously or when the carbamazepine was stopped. One patient with palatal myoclonus, refractory to all other forms of treatment, had complete relief on a small dose of carbamazepine. It may be that palatal myoclonus, hemifacial spasm, and other such clonic convulsive disorders will be amenable to the same treatment.

Administration, Oral↗
PubMed1978

Ventilation of the atelectatic ear.

The absorption of gas from the middle ear--mastoid air cell system causes an average pressure decrease of 5 cm water per hour. Interference with the normal opening of the Eustachian tube causes increased negative pressure build-up, which stops gas absorption from the middle ear. High carbon dioxide tension is associated with metaplastic changes of mucosal stem cells into mucus producing cells. Ventilation of the middle ear is necessary for removal of the negative pressure as well as of the excess carbon dioxide. The problems associated with longterm ventilation tubes are reviewed, and some future prospects of permanent ventilation tubes are discussed.

Biocompatible Materials↗
PubMed1978

Hazards of ventilation tubes.

Ventilation tubes are not the treatment of choice in serous otitis media. Conservative measures should be tried first, with simple myringotomy for the evacuation of thick, rubbery fluids. Autoinflation, well tolerated by most children above 3 years of age, should be practiced daily for months to years, under periodic check-ups. Tube insertion should be reserved for younger children, as well as for recurrent and non-responsive cases. These are the cases in which a calculated risk is worth taking, as otherwise the patient is on an ineffective treatment. In those hard-to-manage ears, tubes seem to be justified, as their potential hazards are apparently outnumbered by the complication of untreated or maltreated serous otitis media.

Atrophy↗
PubMed1978

Bilateral sudden deafness following combined insecticide poisoning.

A case of combined poisoning due to exposure to an aerosol containing both malathion and methoxychlor (sold under the trade name Ortho TM Orchard Spray in the United States) ps presented. The following unusual features occurred in the course and outcome of the poisoning: slow onset of symptoms and signs, bilateral profound and permanent sensorineural hearing loss, and residual peripheral neuropathies in the extremites. The possible potentiation of the usually low toxicity of malathion is suggest and discussed.

Adult↗
PubMed1977

Evaluation of diatrizoate meglumine (Hypaque) in treatment of sudden hearing loss.

Thirty patients with sudden hearing loss were treated with diatrizoate meglumine (Hypaque) and a vasodilator regimen. Of these patients, 30% had a good response, 23% had a moderate response, and 47% had no response. These results were superior to the results obtained in a group of patients with sudden hearing loss treated with vasodilators alone. A possible mode of action is discussed and the details of a new study outlined.

Adult↗
PubMedDate not supplied

Treatment of sudden hearing loss with diatrizoate meglumine (Hypaque).

Between March and November 1976, 30 patients with sudden hearing loss (SHL) were treated with vasodilators and diatrizoate meglumine (Hypaque). Nine (30%) of the patients had a good response, 7 (23%) had a moderate response, and 14 (47%) had no response to treatment. Most of the patients who responded were treated within the first month and had no vertigo associated on their onset of SHL. Their hearing loss was also less than 90 dB for any of the frequencies tested. Using the criteria of SHL of less than one month's duration, no vertigo associated with onset, and a loss less than 90 dB, seven patients were treated with vasodilator plus Hypaque during the period between January and August 1977. Six (86%) of the seven patients had return of serviceable hearing.

Adult↗