Search PubMed⌕ Search

Biomedical subjects

M Hardy

Publications and source records attributed to M Hardy.

132 records · Page 8Linked to original sources
PubMedDate not supplied

Integrating herbs and botanicals into patient care.

Consumer use of herb and botanical preparations is burgeoning. Many common herbal remedies have proven efficacy, reported mainly in the European scientific literature. Although not mandated by law, responsible manufacturers of herbal products are working to establish efficacy, safety, and good manufacturing standards. Pharmacists should be alert for possible drug interactions between phytomedicines and pharmaceuticals, as well as potential adverse effects. Well-informed pharmacists can provide useful counseling and education about herbs and botanicals.

Patient Education as Topic↗
PubMedDate not supplied

The effect of GYKI-32 887 on dopamine (D2) and serotonin (5-HT1 and 5-HT2) receptors.

Investigations were carried out with a dopamine agonist compound GYKI-32 887 to compare its binding capacity towards D2, 5-HT1 and 5-HT2 receptors. Synaptosomal membranes were prepared from corpus striatum, hippocampus and frontal cortex of rats. The tritiated ligands used were: 3H-spiperone for D2 and 5-HT2 receptors and 3H-5-HT for 5-HT1 receptors. Comparing the results obtained, IC50 and Ki values, one can conclude that GYKI-32 887 has higher affinity towards D2 receptors than serotonin ones and shows better selectivity than bromocriptine, the reference substance.

Animals↗