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Biomedical subjects

M Harasawa

Publications and source records attributed to M Harasawa.

At least 55 records · Page 3Linked to original sources

Effect of dihydroergotoxine on activities of beta-receptor stimulators.

The effect of dihydroergotoxine (DET), an alpha-receptor blocker, on the bronchodilating effect of various beta-receptor stimulators was examined using the isolated guinea-pig tracheal smooth muscle. Relaxation of isolated guinea-pig tracheal smooth muscle with isoproterenol hydrochloride, salbutamol hemisulfate and clorprenaline hydrochloride, was markedly increased by continous infusion of DET. This result may suggest that DET, an alpha-receptor blocker, can be used together with bronchodilators such as beta-receptor stimulator for the treatment of various chronic obstructive pulmonary diseases.

Adrenergic beta-Agonists↗