The authors present an attempt to develop methodological points of view on studies of changes in mental functions after various forms of anaesthesia and operation, e.g. open-heart operations. The value of results from unoperated control patients examined with the same methods and at the same intervals, is pointed out. Intraindividual changes in scores from pretest to post-tests seem to be the best measure of postoperative mental functions. For a more accurate appraisal of the results in a material of this kind, it is also recommended to make only a limited number of basic tests of specified hypotheses. For many investigations in this field para metric methods are unsuitable and nonparametric statics should therefore be preferred.

Anesthesia, General↗

PubMed1976

A case-referent study on neuropsychiatric disorders among workers exposed to solvents.

Published reports give justification for the belief that long-term exposure to solvents might induce chronic but nonspecific neuropsychiatric conditions. This case-referent study of data from a regional Swedish pension fund register indicated a risk ration of 1.8 in regard to nonspecific neuropsychiatric disorders among workers such as painters, varnishers and carpetlayers who are exposed to solvents as compared to workers not so exposed. Moreover a dose-response relationship seems to exist between exposure in terms of occupational years and neuropsychiatric conditions, the result being that persons affected are considered eligible for disability pensions.

Adult↗

PubMed1975

[Mental function changes among house painters].

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Cognition Disorders↗