[Thoracic computerized tomography].
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Biomedical subjects
Publications and source records attributed to M Haertel.
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In computer tomography of the abdomen the amount of diagnostic information obtained depends on the organ system examined and correlates with the topographical anatomy. The information gained by this non-invasive method results from the demonstration of contour alteration and from inherent density differences. Although at this point in time, while the process of evaluation is still in progress, it is too early to formulate definitive guidelines on the indications for computer tomography of the abdomen, we suggest, on the basis of experience hitherto, that computer tomography of the adrenals and the pancreas is better than the previously known image-producing diagnostic methods. The overall diagnostic value of computer tomography of the liver and spleen, depending on the pathology in question, is apparently at least equal to sonography, nuclear medicine and angiography. Computer tomography of the gastrointestinal tract and the kidneys, when compared to other diagnostic radiographic and sonographic investigations, at present adds little information, and for this reason has limited application in these systems. In contrast to this is the highly instructive computer tomographic examination of the extrarenal retroperitoneal space.
Using the formulae of Fazio and coworkers, we calculated the extravascular lung water per unit of blood volume (ELW/V) and per unit of blood flow (ELW/F) after intravenous injection of 113In-transferrin as the blood label, and 123I-antipyrine as the diffusible, i.e. water label. Time-activity curves were recorded over the right anterior upper chest wall using a mobile detector. The curves were digitalized and fitted to a gamma-variate using a GAMMA-11 computer. Area over height calculations gave the mean transit times (t). Sixteen control subjects, without evidence of cardiac or pulmonary disease, and 10 patients, with clinical and radiological evidence of left heart failure, were examined. In the control group ELW/V was 0.37 plus or minus 0.17 and ELW/F 3.39 plus or minus 1.56 (mean plus or minus 1 SD). In the patients ELW/V was 0.71 plus or minus 0.26 and ELW/F 13.10 plus or minus 5.67. The difference between both ELW/V and ELW/F for the control group and the patient group is statistically significant. Our values for ELW/V both in patients and control subjects are very similar to those obtained by Fazio and coworkers using H2 15O. However, our values for ELW/F differed from those of Fazio; this could be partly due to dependence of this parameter on the cardiac output.
The normal appearances of the pancreas as seen on computerised tomograms (EMI) has been demonstrated in fifty normal patients and correlated with fifteen post mortem studies on patients with a normal pancreas. The problems of optimal demonstration of the pancreas on computerised tomograms and possible sources of error in the interpretation of transverse pancreas tomograms are discussed.
The radiological features of congenital choledochal cysts are discussed with reference to three cases seen by the authors. The diagnostic problems are mentioned, and use of scintigraphy and ultrasound tomography at an early stage is recommended in order to define more clearly the indications for invasive radiological methods.
Based on a retrospective study of 14 patients with pancreatic pseudocysts, the ultrasonic evaluation of the pancreas is discussed and correlated to the conventional radiologic, endoscopic and angiographic examinations. The pancreatic sonography, as a non-invasive examination, is the method of choice for pancreatic screening and is recommended whenever a pancreatic pseudocyst is suspected.
The radiological features of cystic and alveolar echinococcal disease of the liver is described, based on 17 patients. Conventional radiographs, liver ultrasound and liver angiography are described.
The radiological morphology of indirect rupture of the diaphragm is described; this may be followed by transdiaphragmatic prolapse of viscera, possibly complicated by strangulation or incarceration. The differential diagnosis is discussed with reference to fifteen cases seen by the author(s).
The sonographic-radiological diagnosis of abdominal abscesses is discussed; these are divided into intraparenchymal, extra-parenchymal-intraperitoneal and extraparenchymal-extraperitoneal lesions. The results of grey scle sonography are most informative and are correlated with the radiological and scintigraphic findings in 25 patients. In addition to the advantages of economy and of a non-invasive method, ultrasound permits aimed fine-needle aspiration of pathological abdominal processes such as abscesses.
The radiological appearances of fibro-epithelial polyps of the ureter are demonstrated by four cases and the differential diagnosis is discussed. These mesenchymal tumors are characterised by their variable position and change in shape during the course of a retrograde pyelogram; they appear as smooth intraluminal filling defects with a narrow base and occasionally a racemose pattern. In general, they do not cause ureteric obstruction--and are more common on the left and in the proximal ureter.
Twelve patients were examined by sonography and phlebography; of these, ten had suprarenal tumours and two suprarenal hyperplasia. The value of sonography and its place compared with radiological examinations is discussed. Sonography is an informative method of screening and should be employed whenever there is clinical suspicion of enlargement of the suprarenals before other radiological methods are used.
Transcatheter therapeutic arterial embolization with Spongostan was performed in 10 patients with inoperable malignant tumors of the urinary tract. It resulted in prompt and to some extent permanent relief and/or reduction of local tumor symptoms. Despite frequent transient side effects following occlusion, no permanent or serious complications have been directly attributable to the embolization.
The angiographic appearances of malignant liver cell tumours are described. The differential diagnosis between hepatoblastomas and hepatocellular carcinoma is discussed with reference to ten patients seen by the authors, the difference depending on the maturity of the liver tissue undergoing malignant change.
The normal anatomy of the pancreas is demonstrated by computed tomography (CT) (EMI) in 50 patients with no known pancreatic disease and in 15 comparable postmortem studies. The problems of optimal demonstration of the pancreas in CT and the possible causes of misinterpretation of the pancreatic axial tomography are considered. The size of the normal pancreas was found to be up to 3.0 cm for the head, 2.5 cm for the neck and body, and 2.0 cm for the tail. In assessing these values, it is important to be sure that adjacent structures such as the portal vein, splenic vein, and duodenum are not included in the measurement, that the measurements are taken on scans of maximum resolution with no movements, and that the measurements are strictly related to the anteroposterior diameter. It is considered that gantry tilt will also distort these figures. The reasons for these statements are presented and discussed.
A study is presented of four female patients with congenital solitary liver cyst. The largest cyst had a volume of 4 liters. One of the patients studied had a neoplasm which was possibly the result of secondary malignant degeneration of the cyst. Congenital cystic degeneration may develop in the entire biliary tract. The clinical symptoms depend on the size, localization and number of cysts. Characteristic signs and symptoms caused by displacement of the intestinal organs begin to appear as a rule in late adulthood. The cysts rarely impair liver function. Hemorrhage into the cysts, rupture of the cystic wall, infection or secondary malignant degeneration of the cysts, torsion and strangulation are infrequent. Solitary cysts of the liver are not accompanied by cysts in other organs as is the case in polycystic liver disease. Diagnostic procedures, differential, diagnosis and therapeutic measures are discussed, and reference is made to non-congenital cystic formations in the liver.
The angiographic appearances of biliary neoplasms and their differential diagnosis is discussed in relation to 15 patients with annular carcinomas of the gall bladder or bile ducts. The outstanding angiographic features of biliary carcinomas are irregularities of the arterial contours and vascular occlusion, followed in importance by neo-vascularity of the malignant tumour.
The angiographic morphology for various arterial injuries is described and illustrated by means of 46 patients examined by us; these consisted of 13 socclusions, 21 arterial rupture and 12 arterial lacerations. The main angiographic feature is thrombotic occlusion of the damaged artery. Consequently, the pathology of the arterial lesion could be defined in only one third of the patients with arterial injuries. This, however, is not of major importance in planning vascular surgery.
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