Search PubMed⌕ Search

Biomedical subjects

M Haertel

Publications and source records attributed to M Haertel.

At least 37 records · Page 2Linked to original sources
PubMed1985

[The clinical pharmacokinetics of allopurinol. 1. Allopurinol absorption sites and dose proportionality of allopurinol/oxipurinol bioavailability].

The rate and extent of allopurinol absorption was studied following its oral ingestion in a "high frequency capsule" which allows the evaluation of the sites of drug absorption. If allopurinol is liberated in the duodenum or upper jejunum its absorption is fast and complete while its liberation in the lower jejunum results in a slow and incomplete absorption. A capacity limited absorption process for allopurinol, suggested from the results of a study on the allopurinol bioavailability from different formulations, could not be proved in the range of single doses between 200 and 600 mg resp. 2.2 to 12.8 mg/kg. AUC- and Cp-values of allopurinol and oxipurinol correspond to the calculated figures in relation to the different doses/kg.

Adult↗
PubMed1985

[Normal anatomic measurements in cervical computed tomograms].

Radiodiagnostically relevant normal values and variations for measurements of the cervical region, the arithmetical average and the standard deviation were determined from adequate computer tomograms on 60 healthy women and men, aged 20 to 83 years. The sagittal diameter of the prevertebral soft tissue and the lumina of the upper respiratory tract were evaluated at exactly defined levels between the hyoid bone and the incisura jugularis stuni. The thickness of the aryepiglottic folds, the maximal sagittal and transverse diameters of the thyroid gland and the calibre of the great cervical vessels were defined. To assess information about laryngeal function in computerized tomography, measurements of distances between the cervical spine and anatomical fixed points of the larynx and hypopharynx were made as well as of the degree of vocal cord movement during normal respiration and phonation.

Adult↗
PubMed1984

[Computed tomography of pancreatic cystic fibrosis].

The computer tomographic appearances of atrophic and lipomatous degeneration of the pancreas in cystic pancreatic fibrosis are described. CT exploration of the pancreas is recommended, particularly in differential diagnostic aspects of cystic fibrosis.

Adolescent↗
PubMed1984

[The cervical compartments in the computed tomogram].

The computed tomographic anatomy of the cervical compartments, with emphasis on the fascial planes of the neck, is described. Typical disease processes within these fascial confined compartments have been documented.

Adolescent↗
PubMed1984

[Computed tomography of laryngoceles].

The computer tomographic appearances of internal, external and mixed laryngoceles are described on the basis of ten patients and the differential diagnosis is considered.

Adult↗
PubMed1984

[Computed tomography in cervical lymphadenopathies].

The computer tomographic appearances of cervical lymphadenopathies were studied in 130 patients with special reference to differential diagnosis. The volume and contour of the lymph nodes, their radiosensitivity and contrast enhancement were judged for differential diagnostic purposes.

Humans↗
PubMed1984

[Computed tomography in ruptured abdominal aortic aneurysms].

The computer tomographic appearances of ruptured abdominal aortic aneurysms are described, with particular reference to localisation and haematoma formation. Emergency CT is recommended as the method of choice for investigating ruptured abdominal aortic aneurysms because of the wealth of information and high diagnostic precision.

Aged↗
PubMed1983

[Computer tomographic functional diagnosis of the larynx].

The computer tomographic morphology of the larynx was studied in 19 patients during various phases of respiration, such as during quiet breathing and in expiratory phonation. The diagnostic information which can be obtained by computer tomographic functional studies of laryngeal neoplasms is discussed.

Adult↗
PubMed1982

Computed tomography in staging of carcinoma of the urinary bladder.

Seventy-seven patients with carcinoma of the urinary bladder were investigated by computed tomography (CT) and the results compared with those of pathological staging. The overall accuracy rate was 81% for the estimation of local tumour extension. Perivesical tumour extension was overestimated by CT owing to previous bladder surgery or radiotherapy in about half of the cases. Nevertheless, CT gives unrivalled diagnostic information in advanced tumour invasion. The diagnostic accuracy rate of CT in the detection of lymph node metastases was 89%, compared with 73% for lymphography.

Adult↗
PubMed1982

Lasting improvement of renovascular hypertension by transluminal dilatation of atherosclerotic and nonatherosclerotic renal artery stenoses. A follow-up study.

Sixteen consecutive patients with renovascular hypertension were treated by transluminal dilatation and observed during 6 - 39 months (mean 21.8 months). Poststenotic renal artery pressure increased (p less than 0.001) and the renal arteries were patent on angiograms taken immediately after dilatation. In 13 patients, angiography was repeated 2 - 9 months later; at that time the selective renal vein renin ratio had decreased (p less than 0.001). At the end of the follow-up, blood pressure was improved or normal in 14 cases. One of the eight patients with atherosclerosis was normotensive without treatment, compared with five of six patients with fibromuscular dysplasia (p less than 0.05). The results in two cases with vasculitis are uncertain. The four patients with relapses, one after intimal catheter dissection, were treated successfully by redilatation. Thus, renovascular hypertension can be improved by transluminal dilatation in patients with atherosclerosis and in patients with fibromuscular dysplasia with lasting success and a low morbidity rate.

Adult↗