Search PubMed⌕ Search

Biomedical subjects

M Haddad

Publications and source records attributed to M Haddad.

At least 127 records · Page 7Linked to original sources
PubMedDate not supplied

Local application of IGF1 on dental pulp mechanically exposed; in vivo study on rabbit.

IGF1 (Insulin Growth Factor, 1) was intentionally applied onto pulp tissues, aiming to provoque a dentine regeneration process through the stimulation of the dentinoblasts' potententials. 72 cavities were hence performed on rabbit molars, intentionally exposing the dental pulp. Different concentrations of IGF1 were then applied; The histo and anatomo-pathological observations showed persistent vitality of the pulp without any sign of necrosis, even 6 weeks after the IGF1 application. Dentinoblasts layers (as an indication of the regeneration activity) were counted, according to a pre-established protocol, at days 7, 14, 22, 28 and 42. The type of the applied IGF1, was carefully selected to be "Binding Protein Resistant" (IGF-BPR), so to avoid any inhibition of the IGF1 action by the endogenous binding proteins (Hochscheid and coll). The results were conclusive in indicating the IGF1 as an efficient dental pulp capping product.

Animals↗
PubMedDate not supplied

[Hereditary maculopathy in typical retinitis pigmentosa. Apropos of 40 cases].

The authors have studied the hereditary mode of transmission of 40 maculopathy associated to typical pigmentary retinopathy. The genealogic tree was established for each case along with a complete exam. The three types of modes found were: 12.5% dominant autosomal, 15% recessive autosomal, 72.5% sporadic. The authors discussed the different mode of hereditary transmission in a family of three generations. They point out the difficulties of the genetic investigations and concluded that the maculopathy doesn't have a specific transmission mode in the typical retinitis pigmentosa.

Adolescent↗
PubMedDate not supplied

[Acute mesenteric thrombosis. Successful resection and revascularization. Report of a case].

Acute mesenteric thrombosis; resection and successful revascularization. A case report. A patient with acute mesenteric thrombosis was surgically treated with extensive bowel resection and revascularization interposing a synthetic vascular graft. A few months later on aortoduodenal fistula ensued. Critical discussion by the authors of their therapeutic approach with special emphasis on the value of dynamic CT scanning in the evaluation of a functioning synthetic vascular graft.

Aged↗
PubMedDate not supplied

Surgical treatment of limb lymphedema.

Among 286 patients suffering from limb lymphedema seen in the outpatient clinic in the period 1977-1983, 13 were operated upon. The indication for operation and its type were dictated mainly by the gravity of the clinical findings and the failure to respond to conservative measures. Various conservative and surgical regimes are briefly reviewed emphasizing the way they were incorporated into this series. Six patients who underwent excisional operative procedures and five of the seven patients who underwent lymphatic venous bypass procedures benefitted from the operation and the adjuvant therapy.

Adult↗
PubMedDate not supplied

Assessment of surgical residents' competence based on postoperative complications.

The aim of this prospective study was to evaluate surgical residents' operative skills on the assumption that differences in training might have a significant effect on postoperative complications, their type and incidence. This was accomplished using a departmental microcomputer and special non-commercial personally-developed software. There was no significant clinical difference found in the postoperative complication rate in matched groups of patients treated by senior staff and resident staff of the Department. It is suggested that the close supervision by the senior staff might play a role in this outcome. Although analysis of subgroups of patients sustaining moderate to severe postoperative complications showed a statistically significant difference between these surgeon categories, we may consider this difference attributable to the more complex operative problems handled by the senior staff in the same circumstances.

Female↗
PubMedDate not supplied

[Macroglossia].

Explore the source record for details and available documents.

Abscess↗
PubMedDate not supplied

Age profiles of benign gallbladder disease in 2,000 patients.

Hospital charts and operative notes on 2,000 consecutive cholecystectomies performed between 1965-1984 for benign gallbladder disease were reviewed and computer analyzed. Patients were divided into five age categories (1-29, 30-49, 50-69, 70-79, 80 years and above). Fifteen variables were examined for each age category, including total number, sex, presenting symptoms (jaundice, acute cholecystitis, pancreatitis), intraoperative findings (presence of stones, common bile duct width and stones), operative procedures, bile cultures, histology, postoperative course and mortality. In addition to critically assessing performance and permitting comparison with other series, this age-related analysis suggests the following conclusions: The female predominance in age category 1 diminishes in categories 4 and 5. Acute cholecystitis and suppurative cholangitis occur in 44% of age category 5, compared to 14-24% in other age categories. Intraoperative fluorocholangiography is mandatory; common bile duct stones were found in 14% of age category 1. Age category 2 seems to be the group least susceptible to choledochal pathology. Acalculous cholecystitis is closely related to gangrenous changes, especially (almost selectively) in age categories 4 and 5. The frequency of infected bile rises with age, and is found in 90% of patients in age category 5. Mortality from operations for benign gallbladder disease is ten times higher in patients over 70 years of age compared to younger patients. An ultrasonographic study should be performed before any major laparotomy, especially in the aged, in order to diagnose silent stones, and prepare the patient for concomitant cholecystectomy. Elective cholecystectomy in age categories 4 and 5 is still accompanied by high mortality rates.

Adolescent↗
PubMedDate not supplied

The use of far distal arterial bypass for limb salvage.

Thirty-four distal arterial reconstructions to the ankle and the foot for limb salvage were performed in 33 patients, 11 of whom underwent additional operative procedures. The follow-up period is up to 4 years. The operative mortality rate was 9.09%. The 6 month, 1 year and 2 year accumulated patency rates calculated by life table analysis were 85%, 86.7% and 77.3%, respectively. Limb salvage was achieved not only in patients with patent grafts but also in a considerable number of patients whose grafts were occluded between 3 and 24 months postoperatively.

Actuarial Analysis↗