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Biomedical subjects

M Haddad

Publications and source records attributed to M Haddad.

At least 73 records · Page 4Linked to original sources

Primary long-standing chylous reflux into skin: combined operative and non-operative treatment.

Chylous discharge into cavities or skin is rare and usually arises after operations in the vicinity of the cisterna chyli (secondary chylous reflux). When chylous discharge is primary, however, chylous reflux has usually been present since birth probably as a consequence of obstruction to lymph flow at or above the cistern chyli. We report a patient who had had chylous reflux into lacerated skin in a lymphedematous thigh for more than 30 years. The condition was successfully managed using both operative and non-operative methods.

Combined Modality Therapy↗

Rejection of a gelatin-impregnated Dacron graft.

Sealing of the synthetic vascular graft is important to solve problems of leakage. The use of a new vascular graft--Dacron impregnated by gelatin--is described. After operation the patient developed a febrile reaction, and in spite of a thorough investigation no septic foci could be identified. It is believed that the fever was immunological in origin.

Aged↗

[Aortocaval fistula].

Aortocaval fistula is a rare phenomenon which has both acute and chronic clinical presentations. Its diagnosis and treatment are difficult and it presents a surgical challenge of the first degree, requiring intensive perioperative care. A patient with an aortocaval fistula is described. It was found during emergency operation for a ruptured abdominal aortic aneurysm.

Aged↗

Recurrent peripheral arterial occlusion by leukemic cells sedimentation in acute promyelocytic leukemia.

A 10-year-old boy presenting with recurrent successive events of peripheral arterial occlusion in both legs, more prominent on the left side, was diagnosed as having acute promyelocytic leukemia. Histological examination of the occluding material showed that it was composed of leukemic blast cells. The boy underwent five operations. Each time the arterial flow was reestablished by removing cylindrical hollow white material obstructing the lumen. However, after the last operation, irreversible ischemia developed, necessitating an above-knee amputation. There was no evidence of disseminated intravascular coagulation. Three months later a right lumbar sympathectomy was performed for relief of causalgic-ischemic pains, with successful results. Preoperative angiography demonstrated irregular narrowing of the right iliac arteries and tibioperoneal trunk stenosis.

Amputation, Surgical↗

[Candida albicans meningitis and neurosarcoidosis].

We report a clinico-pathological case of neurosarcoidosis characterized by chronic meningitis, intracranial hypertension, bilateral optic atrophy, arthritis and enlargement of liver and lung hilar nodes. Synovial and supraclavicular node biopsies showed multiple non caseating nodules without tubercle bacilli, Candida albicans and Cryptococcus neoformans. Post-mortem examination showed a severe meningeal lymphoplasmocytic infiltration with numerous non-caseating nodules, several giant cells and presence of Candida albicans. There were also a periventricular infiltration of similar cells and numerous cerebral and cerebellar infarctions. We think that the Candida albicans meningitis was a consequence of the immunodepression of sarcoidosis and of corticosteroid therapy.

Adult↗

[Evaluation of non-occurrence by TI-59 programmable calculator].

A TI-59 programmable calculator program is presented for calculating either risk probability, sample size or confidence level (given 2 of the 3 variables) in cases in which an event of concern did not occur, or as expressed mathematically, had zero numerators. Its main usefulness is as a tool for interpreting previously published data containing no adverse event of concern while contemplating medical alternatives. These conditions are not infrequent in rare medical events--either diseases or complications. However, applicability of the program extends beyond these confines, exemplified in experimental planning for considering expected sample size or in calculating certainty in terms of confidence level.

Mathematical Computing↗

Ischemic venous thrombosis.

Eight patients were treated for ischemic venous thrombosis of the extremities. The patients were evaluated retrospectively concerning their history, clinical signs and symptoms, management and follow-up. Neoplastic disease and immobility were the major etiological factors. Once diagnosed, an urgent combined medical and surgical approach proved to be successful in all patients as far as restoration of blood flow to the limb was concerned.

Adult↗

Bilateral versus unilateral high ligation and stripping of the greater saphenous vein for varicose veins.

The problem of long waiting list of patients for varicose vein surgery may be eased by bilateral operation when both limbs are involved and not in two separate operations as is the practice in many surgical centers. We found that patients undergoing unilateral high ligation and stripping did not differ from patients who had bilateral limb operation in terms of complications, morbidity and length of hospitalization. Most of our patients were released after one day of hospitalization. Therefore, we recommend bilateral operation when there is an indication, rather than two unilateral operations.

Female↗

Achievements of physical therapy in patients after modified radical mastectomy compared with quadrantectomy, axillary dissection, and radiation for carcinoma of the breast.

Flexion of the shoulder, abduction, and external rotation in 90 degrees abduction are impaired after operations for breast cancer. We compared postoperative range of motion in 27 patients who underwent modified radical mastectomy and 21 patients who underwent quadrantectomy with axillary dissection and radiation therapy. The patients in the quadrantectomy group demonstrated a significantly higher range of flexion on postoperative day 1 and the day of suture removal. After 3 months, all patients had regained their preoperative range of flexion, with no difference between the groups. The better compliance of the quadrantectomy group to physical therapy may indicate that they suffer less pain and require a briefer or less intensive course of physical therapy.

Adult↗

Unusual presentations of aortoiliac aneurysms.

Unusual presentations of aortoiliac aneurysms may be the reason for a delay in diagnosis of potentially life-threatening conditions. Five such unusual clinical pictures are presented and discussed. The aneurysms were falsely diagnosed as malignant disease, renal colic, sciatic syndrome, intra-abdominal bleeding of unknown origin, and psoas muscle abscess. The medical staff was misled by the atypical complaints, signs and symptoms, which resulted in a dangerous delay in diagnosis. The use of currently available ultrasonography and CAT scans, which enables early diagnosis, depends on the alertness of clinicians when they confront an atypical clinical picture that may be the first clue of a noninnocent aneurysm of the aortoiliac complex. Early surgical intervention before dissection, rupture or fistulization occur ensures a positive outcome and avoids emergency procedures with their attendant high operative mortality and postoperative morbidity.

Aged↗

Retroperitoneal liposarcoma presenting with bilateral leg lymphedema--case report.

The case of a 54-year-old man with a large right retroperitoneal liposarcoma presenting with bilateral leg lymphedema, is reported. Total excision of the tumor resulted in marked reduction of the edema in both legs persisting for four years. Follow-up lymphographies demonstrated lymphatic drainage dysfunction on both sides; nevertheless, the edema did not recur. Based on these findings, a non-compressive hypothesis concerning the evolution of lymphedema in this case is postulated.

Follow-Up Studies↗