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Biomedical subjects

M H Stone

Publications and source records attributed to M H Stone.

At least 145 records · Page 8Linked to original sources
PubMed1982

Diet and exercise in middle-aged men.

Effects of an anaerobic exercise program on serum lipids and lipoproteins in sedentary male subjects were studied for 12 weeks. No dietary changes were made, and individuals were encouraged to maintain their body weight. Increase in lean body weight, decrease in percent body fat, and unchanged total body weight occurred in subjects participating in the resistive weight training program, while the men's serum cholesterol and low-density lipoprotein-cholesterol decreased and their high-density lipoprotein-cholesterol increased. Lipid profile improvements were attributed to exercise.

Adult↗
PubMed1981

Depression in borderline adolescents.

Etiologically, adolescents considered borderline by the criteria in common use are on a continuum between primarily biological and primary psychological disorders. Depression is common, and may be masked (in many cases of ulcer, anorexia, substance abuse, school avoidance) or overt (viz., early onset endogenous depression, hysteroid dysphoria, cases with severe deprivation). Illustrative cases are provided, along with recommendations for treatment.

Adolescent↗
PubMed1979

Assessing vulnerability to schizophrenia or manic-depression in borderline states.

In a discussion of the article on genetic determinants of borderline conditions by Siever and Gunderson, a phenotypic continuum between pure schizotypal and pure affective conditions is postulated. Many "borderline" cases are seen as attenuated forms of schizophrenia, schizoaffective psychosis, or manic-depression. A Venn diagram illustrates differences among syndromes described by Gunderson, Kernberg, Spitzer, and Klein ("hysteroid dysphoria"). Evidence is presented suggesting that Gunderson's borderline syndrome contains more schizotypal individuals than Kernberg's, whereas hysteroid dysphoria is nearer the affective pole of the continuum. A second diagram illustrates how the strength and nature of the genetic factors vary according to the syndrome.

Bipolar Disorder↗
PubMed1979

A psychoanalytic approach to abnormalities of temperament.

Certain personality defects noted during psychoanalytic therapy are expressions of temperament. Using a 72-item temperament index, the author analyzed 101 patients with respect to depressive, irritable, manic, paranoid and shizoid subscales. At least one such "temperament" was present in two-thirds of the borderline and in one-third of the neurotic patients. The temperament-positive borderline patients usually had a close relative with a schizophrenic or primary affective disorder. Several cases exhibiting temperament abnormalities are presented and modifications of analytic psychotherapy to deal more effectively with them are outlined.

Humans↗
PubMed1979

Psychodiagnosis and psychoanalytic psychotherapy.

Patients with conditions in the intermediate range of severity often show adequate capacity to test reality but poor ego integration. To many, a modified psychoanalytic method is often applied. These patients are not easily classified within the standard nomenclature. The term "borderline" has been applied, in an illdefined manner at first; more recently, Kernberg has outlined, in more precise terms, the characteristics of this group from a psychostructural viewpoint. Genetic factors are important in this group also: a family history positive for mental illness is frequently noted. Amenability to analytic therapy is also related to the characterologic subtype, which carries prognostic implications as well. A multidimensional diagnostic approach is therefore crucial in this range of patients. A triaxial model is proposed and described, stressing (a) traditional diagnosis from the standpoint of genetic predisposition, (b) psychostructural diagnosis, and (c) characterological subtype. This method may help resolve confusion about diagnosis in the borderline realm and may lead to more accurate selection of treatment strategy.

Bipolar Disorder↗
PubMed1978

Responses to intensive training and methandrostenelone administration. I. Contractile and performance variables.

The purpose of this study was to investigate the effects of methandrostenelone (Dianabol) on contractile and performance variables in the rat. Thirty-six male Sprague Dawley rats 90 days old were divided into sedentary and exercise groups; they were further subdivided into Dianabol (0.35 mg/kg/day) treated and untreated groups. The exercise groups underwent a program of high intensity training 7 days/week for 6 weeks. Training produced changes in isometric force-time characteristics indicating increased production of tension. Performance test scores increased significantly from 3 weeks to 6 weeks. Performance by exercise and exercise with Dianabol groups was indistinguishable. It is concluded that Dianabol did not significantly alter the adaptations of the rat to high intensity training.

Analysis of Variance↗
PubMed1978

Responses to intensive training and methandrostenelone administration: II. Hormonal, organ weights, muscle weights and body composition.

The hormonal levels of the gonadotropins, the weight of selected organs and of the triceps surae as well as body composition were determined in Sprague Dawley rats at 3 and 6 weeks after intensive training with or without a methandrostenelone (Dianabol) supplement (0.35 mg/kg/day). The controls were sedentary rats of similar age and weight at the start of the experiment. The dianabol treated rats in the sedentary and exercise groups had a depression of plasma LH levels. There were no differences in body weight, specific gravity, lean body weight, fat or %fat between the two trained groups. Dianabol had no apparent effect on the measured parameters other than a depression of LH.

Analysis of Variance↗