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Biomedical subjects

M H Moore

Publications and source records attributed to M H Moore.

88 records · Page 5Linked to original sources
PubMed1986

Diagnosis of systemic polyarteritis nodosa following total abdominal hysterectomy and bilateral salpingo-oophorectomy: a case report.

We describe a case of polyarteritis nodosa in a 66-year-old woman who presented with multiple neurologic complaints. The case remained perplexing to the clinicians caring for her until a total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed for a right adnexal mass noted on physical examination and computed tomography scan. Although unsuspected polyarteritis nodosa has been diagnosed on examination of other tissues removed at surgery, this is the first case of polyarteritis nodosa diagnosed following total abdominal hysterectomy and bilateral salpingo-oophorectomy reported in the English literature.

Aged↗
PubMed1986

Elbow coverage.

Explore the source record for details and available documents.

Aged↗
PubMed1985

The hairless osteotomized radial forearm flap.

A case is reported demonstrating that the radial osteocutaneous free flap can be "ill-treated" by excision of its hairy skin and split-skin grafting prior to transfer and osteotomy of its bony element during transfer without apparent adverse effect.

Carcinoma, Squamous Cell↗
PubMed1984

Campylobacter enteritis in the acute surgical ward.

Campylobacter jejuni now represents an important cause of acute infectious diarrhoeal illness. This paper examines the clinical course and management of eight patients, with campylobacter enteritis, presenting as acute surgical admissions. The severity of their symptoms and signs provided difficulty in distinguishing this diagnosis from acute surgical emergencies, in particular acute appendicitis. One patient underwent a laparotomy--a normal appendicectomy.

Abdomen, Acute↗
PubMed1983

Transient immunologic effects of betamethasone in human pregnancy after suppression of preterm labor.

Maternal immune suppression is a potentially significant adverse effect when betamethasone is used to hasten lung maturation of the fetus at risk for preterm delivery. However, increased incidence of infection has not been observed consistently after betamethasone treatment of pregnant women. This study was designed to determine if the cellular immune response to steroids may be modified during pregnancy in a way that would diminish the infection risk associated with steroid treatment. The effect of betamethasone on immunocytes among patients with preterm labor or in nonpregnant subjects were determined following administration of 12 mg of betamethasone intramuscularly. We measured serially the circulating leukocytes, lymphocytes, T lymphocytes, and their subsets. Measurements were also made of localized leukocyte mobilization to serum-filled skin chambers covering experimental inflammatory sites. Patients in preterm labor had increased WBC counts prior to treatment with betamethasone but no additional leukocytosis was induced nor was mobilization of leukocytes to the skin chambers decreased. Lymphopenia and depression of T cells was more transient among pregnant patients compared to nonpregnant. Thus, the pregnant patients studied had diminished or more transient potentially adverse immunocyte responses to betamethasone as compared to nonpregnant subjects.

Betamethasone↗
PubMed1982

Early weight gain and glycogen-obligated water during nutritional rehabilitation.

Early weight gain by starving patients managed with total parenteral nutrition has been regarded as spurious - that is, merely an increase in body water. We designed an experiment to mimic the starved state in which glycogen stores are depleted and sodium intake is very low. The subjects were then repleted with a sodium-free, high carbohydrate intake. All subjects who received potassium gained weight and switched to a respiratory exchange ratio which suggested mainly carbohydrate oxidation. From changes in weight and total body water the weight gain was calculated to be the consequence of glycogen storage with 1 g of glycogen obligating 3.21 +/- 0.57 g water. Two patients with total dysphagia showed a similar pattern. Two subjects who did not receive potassium showed a rise in respiratory exchange ratio but failed to store glycogen. Early weight gain in patients who received high-carbohydrate feeding after starvation is a normal phenomenon and represents a return to a more hydrated state consequent upon glycogen repletion.

Body Water↗
PubMed1980

Plasma high-density lipoprotein cholesterol, total cholesterol and triglyceride levels in 17-year-old Jewish residents of Jerusalem: a preliminary report. The Lipid Research Clinics Program Prevalence Study.

Preliminary data on plasma high-density lipoprotein (HDL) cholesterol, total cholesterol and triglyceride levels in 2565 teenage Jerusalem residents attending a military medical examination were analyzed. Mean HDL cholesterol levels were highest among male and female subjects whose fathers had immigrated from Europe and the Americas and lowest in those of Asian and of North African origin. Second-generation Israelis ranked intermediate between the Europeans and the other two groups. Total cholesterol levels were lowest in teenagers of both sexes whose fathers had come from North Africa, highest in subjects of European and of Israeli origin and intermediate in the Asians. Triglyceride levels were also lowest among North Africans of both sexes, but the Asian and Israeli groups had higher mean values than the Europeans. These findings show that patterns of lipid and lipoprotein levels previously observed in adult immigrants persist in a generation of native-born Israelis.

Adolescent↗
PubMed1979

Changes in Harderian gland activity in the female golden hamster during the oestrous cycle, pregnancy and lactation.

The Harderian gland, which is situated within the bony orbit, is usually thought of as a source of lubrication for the eye. However, recent studies have suggested links with reproductive function. In the male golden hamster, both gland histology and activity are known to be under hormonal influence, and the present experiment was undertaken to examine gland weight and activity (as measured by the production of porphyrins) over the oestrous cycle and during pregnancy and early lactation in the female hamster. Gland weight, the number of solid intraluminal porphyrin accretions, and concentrations of copro- and proto-porphyrin were all maximal on day 1 of the cycle (oestrous) and at their lowest on day 2 (or jointly on days 2 and 3), rising gradually thereafter. Porphyrin concentrations are considerably higher during pregnancy and early lactation than during the cycle, and the solid porphyrin accretions, although diminished in number, are larger. Although there is no indication of either the function or the physiological basis of these changes during the cycle or pregnancy, these findings do suggest that in the female golden hamster, as in the male, there is a link between Harderian gland activity and reproductive function.

Animals↗
PubMed1979

Clinical evaluation of the MICRO-ID, API 20E, and conventional media systems for identification of Enterobacteriacea.

MICRO-ID (General Diagnostics, Morris Plains, N.J.) is a new kit system designed for the identification of Enterobacteriaceae in 4 h. It consists of 15 biochemical tests of paper disks. Each test is in its own compartment in a molded plastic tray. Only one reagent need be added to the system (2 drops of 20% KOH, which is added to the Voges-Proskauer test). Based on the pattern of positive and negative biochemical test results, a five-digit octal code number is calculated. An identification is derived from a computer-generated identification manual. A study was conducted to compare three systems-the MICRO-ID 4-h and the API 20E (Analytab Products Inc., Plainview, N.Y.) 18- to 24-h systems and a conventional media system-to measure the ability of each to identify members of the family Enterobacteriaceae. Comparison tables, rather than simple percentage agreement tables, were generated to define the particular strengths and weaknesses of each system and allow the laboratory to best use the data. The MICRO-ID compared quite favorably with conventional media. MICRO-ID yielded incorrect identifications with 1.5% of the isolates tested (API 20E, 4.7% misidentification rate). Half the MICRO-ID misidentifications occurred when the system identified a Citrobacter diversus as a lysine-negative Escherichia coli; all gave one octal number. A direct comparison of the MICRO-ID and API 20E was of limited value because percentage agreements were merely the sums of the errors of each. The ease of inoculation, the requirement for the addition of only one reagent, and the 4-h capability make the MICRO-ID system an extremely attractive development in the field of bacterial identification.

Bacteriological Techniques↗
PubMed1979

Rapid identification of Enterobacteriaceae from blood cultures with the Micro-ID system.

Micro-ID is a new test system designed to identify members of the family Enterobacteriaceae in 4 h. It consists of 15 biochemical tests on reagent-impregnated paper disks; each test is in its own compartment in a molded plastic tray. Based on the pattern of positive and negative biochemical reactions, a five-digit octal code number is calculated. A computer-generated identification manual accompanies the product, and for each octal code listed there is a numerical value that represents the unknown isolate's degree of fit to a typical organism (LFR), a second numerical value that represents its separation from other organisms (PNOR), and a verbal description of the quality of identification. Only one reagent is added to the system. Manufacturer's directions were modified in this laboratory to allow identification from a turbid blood culture bottle within 4 h. Based on 330 routine clinical cultures tested, there was a 96.1% agreement with conventional identification to the genus and species level: 1.2% yielded first two choices possible, with one being the correct choice; 1.2% provided a correct genus, but no species identification; and 1.5% produced an incorrect identification. The Micro-ID is an accurate, facile system for the rapid identification of Enterobacteriaceae from blood cultures.

Bacteriological Techniques↗
PubMed1975

Tooth replacement in the upper jaw of the rainbow trout (Salmo gairdneri).

The present paper describes the pattern of tooth replacement in the upper jaw of two size ranges of rainbow trout (standard lengths 12-15 cm and 20-23 cm) as determined from wax impressions of the dentitions taken twice weekly on anaesthetised fish. There was considerable variation in the nature of replacement waves (lines constructed on dental charts linking eruption times of alternate teeth) between fish for both the premaxillary/maxillary and vomerine/palatine rows. The wave patterns obtained showed the same consistency of form for any one animal which is to be expected when consecutive generations show constant or proportionately changing life spans. Data relating to the life span of the teeth is given. The results are compared with those derived for the lower jaw and the significance of wave form discussed.

Animals↗
PubMed1968

Strychnine and the inhibition of previous performance.

The injection of strychnine sulfate into rats inhibits a hurdle-crossing response. Hurdle-crossing tends to decrease with increasing strychnine doses. The data are interpreted as being consistent with consolidation theory.

Animals↗
PubMedDate not supplied

Soft tissue expansion in the management of the rare craniofacial clefts.

Management of the rare craniofacial clefts requires correction of both the soft tissue and skeletal hypoplasia. Tissue expansion of adjacent and distant soft tissue has been used to reconstruct these facial clefts with like quality tissue. Additionally, such soft tissue expansion permits tension free reconstruction of the skeletal clefts by osteotomy and bone graft.

Abnormalities, Multiple↗