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Biomedical subjects

M H Jaffe

Publications and source records attributed to M H Jaffe.

At least 37 records · Page 2Linked to original sources

The clinical and imaging spectrum of pancreaticoduodenal lymph node enlargement.

Pancreaticoduodenal lymph node enlargement, regardless of cause, has been a source of imaging confusion because of its propensity to mimic pancreatic malignancy yet not cause biliary obstruction. Thirty-eight patients with pancreaticoduodenal adenopathy were imaged with several methods. Pancreaticoduodenal lymphadenopathy could be distinguished from intrinsic pancreatic abnormality on only 44% (14/32) of CT scans and 54% (6/11) of sonograms. Demonstration of intact tissue planes separating adenopathy from pancreas and, to a lesser degree, extrapancreatic vascular displacement were the most helpful diagnostic signs. Surprisingly, 31% of patients had biliary obstruction. Care must be taken in distinguishing metastatic lymphadenopathy from primary pancreatic tumors. The presence or absence of jaundice should not be considered a helpful sign.

Adult↗

Pancreatic imaging.

In this article, the pancreas is evaluated with regard to the controversies surrounding this organ from a clinical standpoint, and an approach to imaging modalities is examined. The roles of computed tomography, ultrasound, endoscopic retrograde cholangiopancreatography, and magnetic resonance imaging are put into proper perspective.

Acute Disease↗

Imaging approach to the suspected renal mass.

The authors present their algorithmic approach to the detection, characterization, and staging of renal masses. Based on classification of urographic findings, the patient may be triaged to the appropriate cross-sectional or invasive imaging modality that will result in the most cost-effective management.

Abscess↗

Hepatic imaging: current status.

The radiologist needs to be aware of the varied appearance of hepatic mass lesions and be prepared to recommend the most cost-effective imaging approach. In this article, the authors discuss their hepatic imaging experience, common pitfalls, and current recommendations.

Biopsy, Needle↗

Controversies in the radiologic diagnosis of pelvic malignancies.

Although vast differences exist among the many pelvic malignancies, several unifying concepts emerge from this discussion. First, there is a different role for diagnostic imaging for each type of pelvic malignancy. The radiologist should be aware that although the radiographic findings may be similar, the clinical impact varies greatly with a particular tumor. Second, although clinical staging is notoriously inaccurate, nevertheless diagnostic imaging techniques only improve upon but do not replace it because of false-positive and false-negative results. Third, because of the high false-negative rates of most of the modalities in use, negative studies do not in fact rule out the presence of disease. A surgical procedure may still be needed. Finally, several new techniques, including MRI and transrectal or transurethral ultrasound, may improve the accuracy rates. These developments will probably further enliven the controversies surrounding the radiologic evaluation of pelvic malignancies.

Female↗

Noninvasive imaging of the gastrointestinal tract.

Numerous radiographic and scintigraphic imaging modalities are now available for evaluating the gastrointestinal system. With a well-formulated plan based on patient history, physical examination, and laboratory values, together with knowledge of patient preparation techniques and consultation, an efficient customized approach to gastrointestinal disease can be accomplished.

Barium Sulfate↗

Imaging of the liver, biliary tract, and pancreas.

The interaction between the various noninvasive and invasive imaging modalities used to evaluate the liver, biliary tract, and pancreas is demonstrated in this article. By understanding this interaction and correlating noninvasive studies, the clinician will avoid diagnostic redundancy and the need for invasive testing may be reduced.

Adenocarcinoma↗

Endoscopic retrograde computed tomography of the pancreas.

Endoscopic retrograde cholangiopancreatography (ERCP) and computed tomography (CT) are well established diagnostic studies for pancreatic evaluation. We conducted a study to determine whether performing these examinations in tandem increased diagnostic accuracy. Patients undergoing ERCP with successful cannulation of the pancreatic duct and who could be placed in the gantry of our CT scanner within 30 min were included in the study. The combined examination, or endoscopic retrograde computed tomography of the pancreas (ERCTP), provided additional useful information in several types of patients including those who had intrapancreatic air without clinical abscess, those with apparent total obstruction of the pancreatic duct on ERCP, and those who were post partial pancreatectomy and were being considered for additional surgery. No additional useful information was provided in patients with a normal ERCP or in routine cases of pancreatitis.

Cholangiopancreatography, Endoscopic Retrograde↗

Hepatobiliary scintigraphy and sonography in early biliary obstruction.

The authors examined 139 patients thought to have early, partial, or intermittent biliary obstruction, using sonography, hepatobiliary scintigraphy, and in selected cases contrast cholangiography. Of 125 patients with a well-established final diagnosis, sonography and scintigraphy disagreed in 29 (23%). Scintigraphy revealed early or low-grade obstruction in 13 patients who had no evidence of dilated ductules, while 7 patients with dilatation from prior stone passage or biliary surgery showed normal clearance. The authors conclude that in a preselected population in whom early or low-grade biliary obstruction may be present, disagreement between sonography and scintigraphy is not rare, and the absence of sonographically detectable dilatation does not exclude obstruction.

Adult↗

Natural history of neonatal periventricular/intraventricular hemorrhage and its complications: sonographic observations.

Cranial sonography is an established procedure for the detection of neonatal intracranial hemorrhage. A 3 year experience in imaging such infants is reviewed. Representative examples are presented to comprehensively illustrate the spectrum of sonographic appearances of intracranial hemorrhage and its complications from the initial hemorrhage to resolution. Diagnostic problems in the initial staging of the grade of hemorrhage and in evaluating subsequent ventricular changes are addressed.

Cerebral Hemorrhage↗

Perirenal cobwebs: the expanding CT differential diagnosis.

Although initially described as representing collateral venous structures, perirenal cobwebs may be due to a variety of benign and malignant conditions. Six representative cases illustrating the broad differential diagnosis are presented.

Aged↗

Sonographic features of uterine leiomyomas: analysis of 41 proven cases.

The relative frequencies of the different sonographic features and patterns of uterine leiomyomas have been examined by prospective and retrospective analyses of the sonograms in 41 proven cases. The original sonographic reports correctly predicted the presence of myomas in 27/45 studies (sensitivity = 60 per cent). Retrospective analyses of the sonograms revealed abnormalities in 32/41 patients (sensitivity = 78 per cent). Most myomatous uteri had two or more sonographic abnormalities, most frequently uterine contour irregularity (76 per cent), altered echo texture (68 per cent) and/or enlargement (66 per cent). Minimal contour irregularity at the interface between the uterus and the bladder deserves emphasis as a subtle diagnostic sign of leiomyoma. Careful attention to the uterus in examining a patient referred for an adnexal mass should improve the diagnostic accuracy of myoma detection by sonography.

Calcinosis↗

Wilms tumor: ultrasonic features, pathologic correlation, and diagnostic pitfalls.

The gray-scale ultrasonic features of Wilms tumor are reported with pathologic comparison. The most consistent ultrasonic features are large size, sharp margination, and echogenic heterogeneity. The frequently observed anechoic areas correlated with hemorrhage and necrosis. A rare case of mesoblastic nephroma is included for comparison. Pitfalls in diagnosis are discussed.

Child↗

Sonography of adrenal pheochromocytomas.

The sonographic features of eight surgically confirmed pheochromocytomas are described and correlated with pathologic findings. The purely solid masses were homogeneous or heterogeneous sonographically. Pathologic examination of the gross specimen provided explanations for the variety of sonographic findings. Two tumors had large cystic components due to old blood. Other hypoechoic areas corresponded to necrosis pathologically. Hyperechoic areas represented hemorrhage. Generally, pheochromocytomas are quite large, sharply marginated, and usually have a significant solid component with or without central necrosis or hemorrhage. Recognition of these features should facilitate their identification on sonography.

Adolescent↗