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Biomedical subjects

M H Faysal

Publications and source records attributed to M H Faysal.

9 recordsLinked to original sources
PubMed1983

Salvage cystectomy.

This report presents the results of 40 salvage cystectomies performed after failure of radiation therapy to control the disease in patients with bladder cancer. All patients had failure or recurrence after 7,000 rad. The time between end of radiation therapy and cystectomy was three to six months in 11 patients, seven to twelve months in 15, thirteen to twenty-four months in 8, and longer than thirty-six months in 6. There were two immediate and four late postoperative deaths. A total of twenty-two complications occurred in 16 patients. The five-year survival rate was 100 per cent for patients with in situ carcinoma, 58 per cent for Stage A disease, 50 per cent for Stage B1, and 40 per cent for Stage B2 disease. There were no survivors among patients with Stages C and D1 disease. Salvage cystectomy, although associated with significant morbidity, remains a viable form of therapy for patients in whom definitive radiotherapy fails.

Carcinoma in Situ↗
PubMed1981

Squamous cell carcinoma of the bladder.

Medical and surgical pathological records were analyzed for 46 patients with pure squamous cell carcinoma of the bladder. Nine patients had metastatic disease at the time of presentation and the remainder had disease limited to the bladder. The 5-year survival figures were 37 per cent for patients with submucosal and/or muscular invasion, and 13 per cent for those with perivesical invasion. No patient with extravesical disease survived 5 years. The best survival figures were encountered in patients who had preoperative radiation therapy followed by total cystectomy and urinary diversion compared to other modalities of treatment. Encouraged by these results we recommend preoperative radiation therapy followed by cystectomy and urinary diversion as the treatment of choice for patients with this uncommon bladder neoplasm.

Aged↗
PubMed1981

Primary neoplasm in vesical diverticula. A report of 12 cases.

Twelve patients with primary carcinoma arising in a vesical diverticulum are presented. Treatment included diverticulectomy with or without post-operative irradiation and transurethral resection. Recurrences were detected in 6 patients and the disease-free survival rate was 8%.

Adult↗
PubMed1980

Urethrectomy in men with transitional cell carcinoma of bladder.

Data on a selected group of 90 male patients who had total cystectomy for diffuse transitional cell carcinoma encroaching on the bladder neck and/or involving the prostatic urethra were studied in relation to the incidence of urethral involvement. Of the 59 patients who had only total cystectomy, 8 (13.5%) required a subsequent therapeutic urethrectomy for clinical anterior urethral carcinoma. Of the remaining 31 patients who underwent simultaneous prophylactic urethrectomy at the time of cystectomy, 2 (6.4%) had transitional cell carcinoma and 1 had moderate mucosal atypia of the anterior urethra. Although the remaining urethra constitutes a potential hazard for further tumor formation, only 1 of 10 patients with urethral carcinoma possibly died of urethral tumor recurrence. Therefore, the urologist has a choice either to follow the patient closely with cytologic urethral wash or to do a prophylactic urethrectomy, especially in patients who are difficult to follow-up closely.

Carcinoma in Situ↗
PubMed1980

The surgical treatment of intractable interstitial cystitis.

Nineteen patients with severe intractable interstitial cystitis were treated surgically with either cecocystoplasty, urinary diversion with or without cystectomy, cystolysis or segmental bladder resection. Of the 6 patients who underwent an augmentation cecocystoplasty 4 were cured and 2 ultimately had urinary diversion before cure. Of the 7 patients who underwent urinary diversion with or without total cystectomy 6 were cured. In the cystolysis group the suprapubic pain was relieved either totally or partially in all 5 cases, and nocturia and urinary frequency were reduced substantially in each. However, only 1 patient was cured completely of all symptoms. The patient who underwent segmental resection of the bladder experienced only temporary symptomatic relief. Postoperative complications included pyocystis in 2 patients who had urinary diversion without cystectomy and hydroureteronephrosis in 1 patient after ureterosigmoidostomy that required multiple procedures. The place for each of these major surgical procedures in the treatment of intractable interstitial cystitis is discussed.

Adult↗
PubMed1979

Evaluation of partial cystectomy for carcinoma of bladder.

We reviewed 117 patients who had undergone partial cystectomy for primary carcinoma of the bladder. The recurrence rate was 78 per cent. Treatment of recurrences included transurethral resection, radiation therapy, and total cystectomy. The five-year survival rate of patients treated for recurrent disease was 68 per cent for Stages 0 and A, 31 percent for Stage B, and 6 per cent for Stages C and D1. Total cystectomy gave the best salvage rate. The five-year survival rate of patients without recurrences was 4 per cent.

Adult↗