Search PubMed⌕ Search

Biomedical subjects

M H Dawson

Publications and source records attributed to M H Dawson.

10 recordsLinked to original sources
PubMed1994

Delayed pain response after lumbar discography.

The delayed onset of symptomatic pain following lumbar discography (with no immediate pain response) is described in six patients, five with a minimum 2-year follow-up. It is usually seen in patients with nearly normal disc morphology who have incomplete or discrete annular tears that are not filled at the time of injection. Later (2-12 h in this study), dye leakage occurs through these lesions, thereby precipitating the discogenic pain. This phenomenon may be missed and is probably more common than previously believed due to early discharge from the hospital, the patient expecting discomfort after the invasive study (hence no complaint is made), and the clinician being unaware of this delayed symptom, thereby not asking about it in follow-up. Close patient questioning regarding a delayed onset of symptomatic pain after discography is, therefore, an essential element in diagnostic information following this study.

Adult↗
PubMed1990

Tuberous sclerosis.

The strong relationship between tuberous sclerosis, cardiac rhabdomyoma, and angiomyolipoma of the kidney is well illustrated in this family case study.

Adult↗
PubMed1986

Simultaneous combined anterior and posterior fusion. A surgical solution for failed spinal surgery with a brief review of the first 150 patients.

Simultaneous combined anterior and posterior fusion (SCAPF) is recommended for patients with severe disability and failed spinal operations. In 150 patients treated over the past five years, emphasis is placed on the evolution of the technique and the surgical principles that exclude decompression of the nerve roots. The available evidence suggests that 86% of the patients were improved; 60% were significantly improved.

Adolescent↗
PubMed1977

Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations.

In a double-blind, randomized trial of orally administered hydroxychloroquine sulphate in the prevention of venous thromboembolism after elective surgery on the hip, the drug or a placebo was given to fifty consecutive patients. Therapy was commenced on the day before the operation and continued for fourteen days. The diagnosis of deep venous thrombosis was made by daily thermographic scanning of the legs and confirmed by phlebography. The diagnosis of pulmonary embolism was made by perfusion lung scanning. No significant difference in the incidence of thromboembolism was found between treated and control groups. The results provide evidence that substances which reduce the incidence of thromboembolism in general surgery may not be effective in operations on the hip.

Administration, Oral↗
PubMed1977

Turnover of collagen in the adult rat after denervation.

Unilateral denervation of the hind limb in a group of adult rats prelabeled with radioactive proline induced a significant turnover of collagen in tendons, ligaments, menisci, and bones. After two or three months of disuse, there were significant losses (15 to 29 per cent) of old collagen from the four structures studied. Dilution of the radioactivity of the old collagen with new collagen involved partial to complete replacement of 3 to 20 per cent. The incomplete replacement of destroyed collagen with new collagen resulted in a net decrease of collagen mass ranging from 5 to 14 per cent. A significant turnover of collagen in two-year-old rats that showed little loss in collagen mass means that the new collagen produced would have fewer cross-links and would probably be weaker than the old, mature collagen.

Animals↗