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Biomedical subjects

M H Cynamon

Publications and source records attributed to M H Cynamon.

62 records · Page 4Linked to original sources
PubMed1982

In vitro comparative activity of moxalactam, GR 20263, and N-formimidoyl thienamycin to other beta-lactam antibiotics and tobramycin against enterobacteriaceae and staphylococci.

The in vitro activities of moxalactam, GR 20263, and N-formimidoyl thienamycin were compared to those of cephalothin, cefazolin, cefamandole, cefoxitin, and tobramycin against 152 strains of Enterobacteriaceae and staphylococci. The results showed that moxalactam, GR 20263, and N-formimidoyl thienamycin each had significantly improved activity toward the gram-negative organisms tested compared to the other beta-lactams and tobramycin. N-formimidoyl thienamycin was particularly impressive with respect to its activity toward Staphylococcus aureus and S. epidermidis as compared to moxalactam, GR 20263 and the older beta-lactam drugs.

Anti-Bacterial Agents↗
PubMed1981

In vitro susceptibility of Mycobacterium fortuitum to cefoxitin.

The in vitro susceptibility of Mycobacterium fortuitum to cefoxitin was studied by agar dilution, broth dilution, and disk diffusion methods. Of 13 isolates, 11 were found to be susceptible by disk diffusion. At a concentration of 25 microgram/ml or lower, all 13 isolates were inhibited when tested by broth dilution, but only 12 of 13 isolates were inhibited when tested by agar dilution.

Cefoxitin↗
PubMed1975

Intentional isoniazid overdosage among southwestern American Indians.

A 30-month study explored the degree to which self-destructive behavior compromised tuberculosis therapy and prophylaxis among southwestern American Indians. The frequency of isoniazid (INH) overdosage paralleled the extent of INH usage in each tribe and the entent to which INH was perscribed for each tuberculosis category. The authors recommend the careful selection of patients for INH prophylaxis, the dispensing of small amounts at short intervals, the close monitoring of patient compliance with the prescribed drug regimen, and, possiblly, the dispensing of individually wrapped tablets to inhibit the impulsive ingestion of massive amounts of the drug.

Administration, Oral↗
PubMedDate not supplied

Mycobacterium gordonae as a human hepato-peritoneal pathogen, with a review of the literature.

Mycobacterium gordonae was cultured from the liver of a 39-year-old woman who presented with ascites, weight loss, and fever. Laparoscopic examination revealed white nodules studding the peritoneum and liver surface, and histopathology revealed caseating granulomas. She was successfully treated with rifampin, ethambutol, and isoniazid. A review of the literature on M. gordonae as a human pathogen in presented. Our patient represents the third reported case of disseminated disease due to this organism and the first to be successfully treated by medical therapy alone.

Adult↗