Search PubMed⌕ Search

Biomedical subjects

M H Becker

Publications and source records attributed to M H Becker.

At least 109 records · Page 6Linked to original sources

Some influences on public participation in a genetic screening program.

To identify the psychosocial factors associated with voluntary cooperation in mass genetic testing, stratified random samples of 500 participants and 500 nonparticipants were drawn from an identified at-risk population for Tay-Sachs disease. Participants were relatively younger and better educated, reported higher levels of perceived susceptibility to being a carrier, and also stated more often that the impact of learning of being a carrier would be low. Participants were also more likely to indicate they would not alter plans for future progeny. Recommendations are made for enhancing participation in future genetic screening programs of this type.

Adolescent↗

Sociobehavioral determinants of compliance with health and medical care recommendations.

Over the past two decades, hundreds of articles, editorials, and commentaries have been published describing the considerable disruptive effects on quality of care of individuals noncompliance with health and medical advice. While much research has been directed at determining factors responsible for poor compliance, past studies have tended to focus upon easily measured characteristics of the patients, regimen, or illness which, unfortunately, are usually neither predictive nor alterable. This paper systematically reviews the literature on patient acceptance of recommended health behaviors, attempting to find social-psychological and related variables which have proven to be consistent predictors of compliance. The review suggests that certain health beliefs (especailly personal estimates of vulnerability to, and seriousness of, the disease, and faith in the efficacy of care), health-related motivations, perceptions of psychological and other costs of the recommended action, various aspects of the doctor-patient relationship, and social influence are the most productive dimensions for present intervention and further exploration. Building upon an earlier formulation, an hypothesized model is presented which combines these elements for explaining and predicting compliance behavior. Further research should, with standardized questionnaires and analysis techniques, employ prospective, experimental designs for a variety of population groups, settings, and regimens, to evaluate the ability of practical attempts to modify the model variables and thus enhance compliance.

Age Factors↗

A new approach to testing the effect of ultrasound on tissue growth and differentiation.

Pulsed ultrasound from a Picker Ultrasonoscopy Model 102, with a frequency of 500 Hz and an energy of 2.2 MHz was applied to the amputated left forelimbs of 24 adult newts. Exposure time was 5 min in half of the animals and 10 min in the remainder. The right forelimbs of these newts were also amputated at the same time, at the same anatomical level, and by the same operator of the left forelimbs, but were not exposed to sonication. Regeneration of both forelimbs was compared and found to be generally slower in the ultrasonicated limb. In 75% there was a definite retardation of growth. The results suggest that the the growth of rapidly proliferating embryonic tissue (newt regenerates are formed from embryonic cells in the stump) is inhibited by ultrasonication.

Animals↗

Bone scanning-osteogenic sarcoma. Correlation with surgical pathology.

This study was designed to evaluate the role of isotopic scanning in determining the local extension of osteosarcoma. During the period of the study, 13 patients wtih biopsy proven osteosarcomas were evaluated. The results indicated that in no case did the isotope scan demonstrate greater intramedullary extension of tumor than the routine roentgenographic examination. In addition, despite good correlation between the roentgenogram, scan, and histologic evaluation of tumor extent, all of which showed no evidence of malignancy near the area of surgery,there have been to date 3 local recurrences.

Adolescent↗

Campomelic dwarfism.

The campomelic syndrome is a short-limb, usually fatal, neonatal dwarfism. It is characterized by bowed lower limbs, especially the tibia, usually associated with a cutaneous dimple over the anterior skin. There is delayed calcification of the epiphyses and delayed mineralization of the spine and pelvis. The cartilages of the tracheobronchial tree are hypoplastic, contributing to death from respiratory problems. Other associated abnormalities are unusual appearing facies, cleft palate, absent olfactory nerves and talipes equinovarus. Less commonly seen are cardiac, renal and brain anomalies.

Adult↗

Clinical and radiographic variations in hemifacial microsomia.

Variations expressed clinically and radiographically in hemifacial microsomia preclude classifying all the abnormalities as coming from the first and second branchial arches. Anatomic structures arising from the branchial arches are directly involved but the final expression results from the combined impact of the primary anatomic defect and the secondary effects on contiguous structures. The deformities resulting from the latter are probably due to abnormal neuromuscular function.

Abnormalities, Multiple↗