Contact dermatitis from spectacle frames and hearing aid containing diethyl phthalate.
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Biomedical subjects
Publications and source records attributed to M H Beck.
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A 4-month-old infant developed a symptomless erythematous maculopapular rash on her abdomen spreading to involve other areas of her trunk and limbs. Skin biopsy showed the features of sarcoidosis and she later developed sarcoid uveitis and arthritis requiring systemic steroid therapy.
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Three thousand consecutive patients undergoing patch tests were tested with a mix of benzocaine, amethocaine hydrochloride and cinchocaine hydrochloride. Eighty-four subjects (2.8%) were found to be allergic to this mix. Forty of these were patch tested with the constituents of the mix: 21 (52.5%) patients were sensitive to amethocaine hydrochloride or cinchocaine hydrochloride or both, but not to benzocaine. We recommend that a non-irritant 'caine mix' containing benzocaine, cinchocaine and amethocaine should be included in the standard patch test series for the U.K.
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7 patients who reacted on patch testing to medicaments, but who had negative reactions to the individual ingredients are described. The possible mechanisms of this phenomenon are discussed.
The incidence of positive patch test reactions to Quaternium 15 has increased by a factor of 3 within a relatively stable population over 2 years, while the incidence of reactions to Bronopol and Germall 115 has remained static. The problem of interpreting an apparent positive reaction to a formaldehyde-releasing preservative in a formaldehyde-sensitive patient is discussed.
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Six ostomy patients presenting with peristomal rashes have been shown to be allergic to their ostomy bags and to epoxy resin. Subsequent investigation confirmed the presence in the bags of low molecular weight epoxy resin oligomers, which are known as potent contact sensitizers.
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