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Biomedical subjects

M Gysel

Publications and source records attributed to M Gysel.

3 recordsLinked to original sources

[Web-based learning tools in pathology].

Pathology is an image based discipline and therefore well suited for web-based teaching. PathoBasiliensis (http://www.unibas.ch/patho/) is a freely accessible internet site addressing various target groups. The site consists of various complementing and constitutive teaching- and information modules. The image database PathoPic represents the central element of the teaching modules. Based on this database teaching modules and learning games have been and are being developed allowing users to exercise diagnostic skills adapted to the individual learning process. Development and evaluation of the online histopathology course HiPaKu and the game Matching pair are presented.

Educational Measurement↗

Hygroscopicity of aerosol particles at low temperatures. 1. New low-temperature H-TDMA instrument: setup and first applications.

A hygroscopicity tandem differential mobility analyzer (H-TDMA) is described that allows a fast and accurate determination of the water uptake by submicrometer aerosol particles at temperatures below 0 degrees C. To avoid volatilization of semivolatile particles, the humidification works without heating the gas stream, and the gas-phase composition is not changed during the analysis. The applied scanning mobility analysis allows a fast and accurate measurement of the humidogram, but care has to be taken with too high scanning velocities leading to artifacts in the particle size measurement. During a field campaign at a high-alpine site (Jungfraujoch, 3580 m above sea level), humidograms of free tropospheric particles were measured at T= -10 degrees C. The hygroscopic growth of these particles was characterized by monomodal growth distributions, which means that in the observed size range (dry particle diameters (Do) = 50-250 nm) the free tropospheric aerosol was to a large extent internally mixed. No distinct deliquescence was observed, indicating that the multicomponent aerosol particles are present in a liquid state even at a low relative humidity (RH) <10%. At RH 85%, average hygroscopic growth factors of 1.44, 1.49, and 1.53 were measured for Do = 50, 100, and 250 nm. The estimated soluble volume fraction of the particles in the observed size range was found to be 0.79, 0.86, and 0.91, respectively.

Aerosols↗

Hygroscopicity of aerosol particles at low temperatures. 2. Theoretical and experimental hygroscopic properties of laboratory generated aerosols.

A Hygroscopicity Tandem Differential Mobility Analyzer (H-TDMA) system has been used to measure hygroscopic growth curves and deliquescence relative humidities (DRH) of laboratory generated (NH4)2SO4, NaCl, and NaNO3 particles at temperatures T= 20 degrees C and -10 degrees C. Good agreement (better than 3.5%) between measured growth curves and Köhler theory was found using empirical temperature and concentration dependent values for water activity, solution density, and surface tension. The measured growth curves only experience a small temperature dependence in the observed temperature range. Therefore, to a first approximation, it is possible to neglect the temperature dependence of the water activity for theoretical calculations in the temperature range -10 degrees C < T < 25 degrees C. The small differences between experiment and theory, which were predominantly observed for NaCl particles, are probably caused by a small amount of water adsorbed on the "dry" crystals. It was also observed that these particles experience a significant restructuring at relative humidity RH < DRH, which was also taken into account for a comparison with theoretical curves. If salt particles are used for instrument calibration, precautions regarding the dry particle diameter have to be taken.

Adsorption↗