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Biomedical subjects

M Grójec

Publications and source records attributed to M Grójec.

At least 19 recordsLinked to original sources
PubMed1989

[Tests evaluating the influence of plasma fatty acid composition on dynamics of the left heart ventricle in children with simple obesity. Part II. The composition of plasma fatty acid percentage and behavior of left heart ventricular contraction in obese children].

Plasma fatty acids contents and dynamics of the left cardiac ventricle contractions were determined in 48 children with simple obesity. Significant deterioration of the dynamics of left ventricle contractions was seen in obese children. It included prolongation of QSIIJ, QI, and PEPI and shortening of LVETI. Correlation of the total contraction time, pre-ejection period and contractility index with plasma saturated and unsaturated fatty acids levels has been demonstrated.

Adolescent↗
PubMed1989

[Tests evaluating the influence of plasma fatty acid composition on the dynamics of contractions of the left heart ventricle in children with simple obesity. Part I. Influence of plasma fatty acid composition in children with simple obesity].

Percent composition of the plasma fatty acids in 48 children with simple obesity was determined with gas-chromatography. Thirty seven healthy, normotensive children served as the control group. An increased content of the saturated fatty acids and decreased content of the unsaturated fatty acids together with the decrease in unsaturated fatty acids:multi-unsaturated fatty acids ratio were seen in children with simple obesity.

Adolescent↗
PubMedDate not supplied

Assessment of the character and incidence of electrocardiographic changes in children with simple obesity.

The studied group comprised 82 children with simple obesity. In the group the character and frequency of ECG changes in 12 conventional leads were analyzed. A correlation was established between the character and frequency of these changes and the degree of overweight and obesity duration. In children with simple obesity a considerable prevalence was observed of disturbances of sinus rhythm, impairment of intraventricular conduction and signs of left ventricular hypertrophy. The observed changes were more frequent in children with over 5 years of obesity duration. No correlation was demonstrated between the incidence of these changes and the degree of overweight.

Adolescent↗
PubMedDate not supplied

Composition of serum fatty acids in healthy children.

In 81 children aged 0-18 years with normal body weight the serum pattern of fatty acids (FA) were determined by means of gas chromatography. The results show that of the 11 FA determined chromatographically, unsaturated and saturated fatty acids had differences in their distribution in the plasma. A certain regularity of these differences in favour of unsaturated fatty acids was observed. At the same time it was demonstrated that the mean values of unsaturated essential fatty acids (EUFA) increased with the age of a child. These results suggest that the plasma FA pattern may be a valuable supplementary source of information about lipid metabolism disturbances in children.

Adolescent↗
PubMedDate not supplied

The composition of fatty acids of the serum and erythrocytes after an alimentary cholesterol load.

The content of certain fatty acids of the serum and erythrocytes was compared in rabbits before and after 11 days on a diet with added cholesterol. The alimentary cholesterol load reduced the levels of linolic and arachidonic acids in the serum, while in the erythrocytes the level of linolic acid was increased. Changes in the levels of the remaining determined fatty acids were not significant statistically.

Animals↗
PubMedDate not supplied

Vasomotor escape from noradrenaline in the renal, mesenteric and hindquarter vascular beds in spontaneously hypertensive rats (SHR).

During 10 minutes of infusion of noradrenaline in doses of 0.1, 0.2, 0.4 and 0.6 micrograms/min into isolated intestinal, kidney and hindquartet preparation, perfused with aerated Tyrode's solution and escape effect was observed in normotensive rats. The escape was significantly reduced in intestinal and renal vascular beds or disappeared in spontaneously hypertensive rats.

Animals↗
PubMedDate not supplied

Levels of linoleic acid and saturated and monounsaturated fatty acids in selected lipid fractions of the serum and platelets in patients with coronary arterial disease.

The levels of serum fatty acids in the serum and in the serum fractions of cholesterol esters (ECH) and triglycerides (TG) and the levels of these acids in these fractions of platelets were compared in healthy controls and in patients with clinically manifested coronary arterial disease. Decreased level of linoleic acid was found in the serum and in the ECH fraction of the serum in the patients, with a rise in the level of palmitic acid in the ECH fraction of the serum of these patients. The level of linoleic acid in the ECH and TG platelet fractions in these patients was not different from that in the healthy controls, while in the platelet TG fraction of the patients the level of palmitoleic acid was raised, and the level of oleic acid was increased in the platelet ECH fraction.

Blood Platelets↗