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Biomedical subjects

M Gonvers

Publications and source records attributed to M Gonvers.

At least 37 records · Page 2Linked to original sources

New approach to managing vitreous loss and dislocated lens fragments during phacoemulsification.

I performed a one-port pars plana vitrectomy during phacoemulsification to manage vitreous loss with and without posterior dislocation of lens fragments in nine consecutive cases. I used a 1 mm vitrectomy instrument with an infusion sleeve for the vitrectomy; the coaxial light of the microscope and an infusion contact lens held on the cornea provided intraocular illumination. Eight of the nine cases achieved a visual acuity equal to or better than 20/25 after a mean follow-up of 5.7 months. One patient's visual acuity was 20/70 because of severe background diabetic retinopathy.

Cataract Extraction↗

[Phacoemulsification with incision of the clear cornea].

METHODS: I reviewed the records of my first 33 phacoemulsifications with a clear cornea incision. The first 3 cases in the series had their temporal corneal incision sutured because of insufficiency in the self-sealing mechanism. RESULTS: Change of refraction induced by surgery was especially studied in 23 cases whose mean follow-up had been 3.5 months. This proved to be very moderate and stable from the first post-operative day up to the last control which took place 5-6 months later. CONCLUSION: The only drawback of the technique, was the occurrence in several cases of anterior capsule fibrosis which seemed related to the nature (silicone) and shape (plate haptics) of the foldable IOL.

Cataract Extraction↗

Sophisticated vitreoretinal surgery in patients with a healthy fellow eye. An 11-year retrospective study.

Forty-four patients who had undergone successful vitreoretinal surgery were included in a retrospective study intended to evaluate the real benefit of surgery in each case. All patients presented with a retinal detachment complicated by proliferative vitreoretinopathy in one eye, the fellow eye being healthy. The number of operations undergone by each patient and the total operating time per patient were carefully recorded. Objective parameters such as visual acuity, visual field and stereoscopic function were monitored. Visual comfort and subjective complaints were graded by means of a questionnaire given to the patients. Any severe event occurring in the fellow eye during the follow-up period was also registered. Sophisticated vitreoretinal surgery in patients with a good fellow eye is useful to the patient if binocular function can be restored at least partially. Correction of unilateral aphakia by a contact lens should not be considered an acceptable solution.

Depth Perception↗

[Pars plana vitrectomy in uveitis].

A vitrectomy was performed in 30 eyes suffering from different forms of uveitis. An improvement of visual acuity was obtained in 29 cases and was explained by removal of vitreous haze and/or of the cataract, but not by the improvement of the inflammatory process.

Adolescent↗

[Ocular toxocara canis in a 30-year-old adult].

Pars plana vitrectomy was performed in a 30-year-old patient who presented a posterior traction detachment due to an inflammatory granuloma. The granuloma removed in toto during surgery revealed characteristic features of toxocariasis lesion (first case described in the literature). An ELISA test performed on a vitreous sample was strongly positive. Retinotomy around the granuloma was necessary to re-attach the retina and silicone oil was used as a tamponade for 4 months. VA improved from HM to 15/200 after silicone removal.

Adult↗

Choroidal metastasis and rhegmatogenous retinal detachment.

The association of a rhegmatogenous retinal detachment (RRD) with a uveal metastasis is an exceptional occurrence. In this article, the authors report the first successfully treated case (to their knowledge) of a patient with one eye in whom both the RRD and the metastasis is treated successfully. The RRD was operated on using a buckling procedure with cryopexy of the retinal break and drainage of the subretinal fluid. The metastasis, originating from an invasive canalicular carcinoma of the breast, was irradiated several days after surgery with a linear accelerator. The primary tumor was treated with systemic hormonotherapy. One and a half years after surgery, the patient is still alive. Visual acuity in the eye is 20/30, the retina is flat and no signs of tumor recurrence have been observed.

Aged↗

Temporary silicone oil tamponade in the treatment of complicated diabetic retinal detachments.

A retrospective study is reported on 132 eyes with retinal detachment, resulting from advanced proliferative diabetic retinopathy, treated using vitrectomy techniques and silicone oil tamponade. Epiretinal surgery was performed using a bimanual technique. Silicone oil was removed in 64 eyes (49%) which regained an improved final vision of 5/200 or better. In 17 eyes (13%), vision was improved but silicone oil could not be removed. It is expected that the function of several of these eyes will eventually deteriorate because of progressive silicone-induced glaucoma. The remaining 51 eyes (38%) were surgical and functional failures.

Diabetic Retinopathy↗

[Surgical treatment of epiretinal macular fibrosis: the Lausanne experience].

Between 1981 and 1988, vitreous surgery was performed on 28 nondiabetic patients with epiretinal macular fibroplasia. The fibroplasia was idiopathic in 9 eyes, occurred after successful surgery for retinal detachment in 10, and was associated with other ocular disorders in 9. The patients were followed up for between 5 and 72 months. While visual acuity improved in 26 cases, metamorphopsia increased in all. The results were poorer in cases where symptoms had already existed for more than 6 months or where not only the retina, but also the macula was detached. Complications were confined to 3 cases in which peripheral tears occurred intraoperatively; there were 2 postoperative retinal detachments. While increased lens opacification was observed in 7 patients, a recurrence was seen only in one.

Adult↗

New instrumentation and technique for epiretinal surgery.

A multifunctional probe for vitreous surgery, which combines fiberoptic endoillumination, microforceps, bipolar diathermy, and infusion/aspiration, has allowed the development of an original technique for the peeling of very adherent preretinal membranes.

Equipment Design↗

The effect of liquid silicone on the rabbit retina. Histologic and ultrastructural study.

Silicone oil was injected into 23 rabbit eyes, which had undergone vitrectomy and which were then examined in the electron microscope six weeks later. Retinal lesions were observed in the outer plexiform layer. They consisted mainly of a subtotal disappearance of the processes of horizontal and bipolar cells and of the synaptic terminals of the photoreceptors. The lesions were seen only in areas of the retina that had been in permanent contact with the oil bubble. They did not depend on the purity of the silicone oil injected.

Animals↗

Temporary silicone oil tamponade in the management of retinal detachment with proliferative vitreoretinopathy.

Silicone oil was used as a temporary (four to six weeks) tamponade in conjunction with vitreous surgery in the management of 146 eyes with retinal detachment complicated by proliferative vitreoretinopathy. A success rate of 62% (90 of 146 cases) was achieved six months after the silicone was removed. Clinical complications directly related to silicone oil were rare and did not progress or develop after the removal of silicone except for opacification of the lens in phakic eyes. This occurred frequently (43 of 55 eyes) and progressed many months after the withdrawal of silicone.

Eye Diseases↗

Temporary use of silicone oil in the treatment of proliferative vitreoretinopathy. An experimental study with a new animal model.

Homologous fibroblasts were injected into vitrectomized rabbit eyes. This injection produced a total retinal detachment in all ten eyes of a control series. In each case the detachment was due to the contraction of a membrane which had grown on the retinal surface as seen in human proliferative vitreoretinopathy (PVR). In another group of ten eyes, silicone oil was injected before the fibroblastic membrane contracted, and removed again a few weeks later. This temporary tamponade of silicone oil reduced the rate of detachment to 50%. Silicone oil did not prevent the preretinal membrane from growing but mechanically decreased its contraction.

Animals↗

Temporary use of silicone oil in the treatment of special cases of retinal detachment.

Temporary use of intraocular silicone oil has first been described for the treatment of retinal detachments with massive periretinal proliferation. The technique has been proved to be safe and helpful and is now used for the management of other desperate retinal detachments, such as those with traumatic fibrous ingrowth, giant tear, posterior hole, and choroidal coloboma.

Choroid↗

A new approach to treating retinal detachment with macular hole.

Six consecutive cases of retinal detachment with macular hole were treated successfully by vitrectomy, partial gas-fluid exchange, and prone positioning of the patient for 12 hours. Macular coagulation and macular buckling were not necessary. In five cases the retina remained flat during follow-up periods ranging from one to 16 months. In one case a small detachment recurred 13 months after surgery. A renewed partial gas-fluid exchange resolved the problem. This new technique simplifies the treatment of such cases and macular function is preserved rather than destroyed. We believe than many detachments with macular holes are caused by vitreous traction.

Aged↗

Temporary use of intraocular silicone oil in the treatment of detachment with massive periretinal proliferation. Preliminary report.

A new approach in the treatment of retinal detachment complicated by massive periretinal proliferation is described. The surgical procedure combines pars plana vitrectomy with temporary use of silicone oil injection and panretinal photocoagulation. The anatomical success rate for a small series of 21 eyes was 57% after removal of the silicone oil. The 12 eyes presenting a successfully reapplied retina recovered useful visual acuity.

Administration, Topical↗