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Biomedical subjects

M Glasser

Publications and source records attributed to M Glasser.

At least 73 records · Page 4Linked to original sources
PubMed1977

Homosexuality in adolescence.

This paper asserts that homosexuality in adolescence should not be regarded in the same way it would be in adults. Different types of homosexuality emerge during adolescence according to the different psychodynamic conditions which occur at different stages of adolescence, particularly the changing relationship to the individual's parents, and these may subside or make an important contribution to the establishment and nature of an individuals' homosexuality in adulthood. The characteristic 'identificatory facility' of adolescence is discussed and it is suggested that this is retained in the make-up of the adult homosexual. Some comments on the clinical assessment of homosexuality in adolescence are briefly made.

Adolescent↗
PubMed1976

Contraceptives and the conceptus. I. Chromosome abnormalities of the fetus and neonate related to maternal contraceptive history.

The chromosomes of 3080 products of conception, consisting primarily of newborn infants and medically induced abortions, were examined. These were from 3 major groups of women, those who had used oral contraceptives (primarily the combination types), those who had used nonhormonal contraceptives, and a control group of those who had not used any contraceptives. In the newborn study population, the chromosome abnormality rate was 5.4 per 1000 infants (when cases of proven hereditary involvement are excluded the figure drops to 3.6 per 1000), and in the entire induced-abortion study series it was 7.3 per 1000. These rates are very similar to those obtained in other surveys. The rate of chromosomally abnormal conceptuses increases with increasing maternal age in both the newborn and induced-abortion groups. No statistically significant relationships were found between the observed or age-adjusted rates of chromosome abnormalities and contraceptive history (P greater than .10 in all cases). The findings make it clear that the use of oral contraceptives has no large effect on the risk of having a chromosomally abnormal child although the possibility of a small increase or decrease in this risk, of at most about 10 per 1000, cannot be ruled out because of the small number of abnormalities found.

Abnormalities, Drug-Induced↗
PubMed1975

Self-regulated methadone detoxification of heroin addicts. An improved technique in an inpatient setting.

We used a method of detoxifying heroin addicts involving a self-regulated schedule of methadone hydrochloride detoxification in an inpatient setting. This method allows the addict to receive methadone on an "as needed" basis within specified guidelines, thus permitting him to regulate his own detoxification. For this study, 30 chronic heroin addicts were detoxified using this self-regulated detoxification procedure. Measures of length of stay, amount of methadone required, and degree of patient satisfaction indicate that this is a practical means of withdrawing chronic heroin addicts that may have advantages over fixed withdrawal schedules.

Adult↗
PubMed1975

Chromosome polymorphism in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual.

Replicate chromosome preparations of umbilical-cord-blood leukocytes from 376 neonates born at the Albert Einstein College Hospital, Bronx, New York, were stained with C-, Q-, and G-banding methods to determine the frequencies and distributions of the variable chromosome bands. The C-band variants of primarily chromosomes 1, 9, and 16, as well as those of the remaining C, E, and F-group chromosomes, and the brightly fluorescing Q-band variants of chromosomes 3 and 4 and all of the acrocentrics, including the Y, were similarly analyzed. Polymorphism of these chromosome regions was so extensive that the idiogram of each of the 376 newborns of this study had a unique variant pattern, even when only the C- or only the Q-band patterns were compared. The distribution of polymorphic Q-bands in the population sampled was consistent with the expectations of the Hardy-Weinberg law, with the exception of chromosomes 3 and 22, where some deficiency of individuals with "homozygous" Q-band patterns was found. The baseline data presented here reinforce the view that polymorphic chromosome characteristics are very useful markers for characterizing the karyotype of an individual, for pedigree studies, for prenatal chromosome analyses, for population studies, for attempts at gene localizations, and for identifying specific cells or their chromosomes in somatic cell genetic studies.

Chromosome Mapping↗
PubMed1975

Out-patient cataract surgery.

A randomized prospective study of 100 consecutive cataract operations was designed to ascertain the need for hospitalization for this procedure. The results clearly indicate that immediate ambulation and discharge of the cataract patient do not detract from the very high success rate of this operation. The random nature of this study adds strong support to those surveys that have similarly concluded that hospitalization and postoperative restrictions are not necessary for the great majority of cataract patients.

Adult↗