Biomedical subjects
M Gillies
Publications and source records attributed to M Gillies.
Local interferon alfa-2b for ocular cicatricial pemphigoid.
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Interferon-alpha 2b inhibits proliferation of human Tenon's capsule fibroblasts.
To evaluate the potential of interferon-alpha 2b (IFN-alpha) as an antifibrotic treatment after glaucoma filtering surgery, we studied its ability to inhibit mitogen-induced proliferation of human Tenon's capsule fibroblasts in vitro, as shown by [3H]-thymidine incorporation. IFN-alpha inhibited fetal calf serum-induced proliferation in a dose-dependent manner in concentrations ranging from 10 to 10,000 IU/ml (P < 0.001). Inhibition was also found when IFN-alpha was added prior to the mitogen (P = 0.001); this inhibitory effect lasted at least 3 days. We suggest that IFN-alpha deserves further evaluation as a possible agent for the control of ocular fibrosis.
Haemophilus influenzae type b disease in Auckland children 1981-87.
Haemophilus influenzae type b invasive disease was reviewed in the Auckland paediatric population. A total of 205 episodes were confirmed by sterile cavity culture in 203 patients under 15 years of age over a seven year period. The incidence of invasive disease was 14/100,000/year in those under 15 years and 41/100,000/year in under 5 year olds. The age range was from 1 month to 11 years, with 91% under 5 years and 64% under 2 years. Most cases were due to meningitis (63%). Other diseases included epiglottitis, pneumonia, cellulitis, arthritis, and occult bacteraemia. There was only one fatality. Beta lactamase production was found in 9% of meningeal isolates. Recently a new conjugated haemophilus vaccine has been licensed in the United States for use in children 18 months and older. Consideration should be given to introducing this vaccine in New Zealand.
Detection of Campylobacter pyloridis infection.
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Comparison of the antistaphylococcal activity of serum from healthy subjects taking flucloxacillin or augmentin.
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Scurvy and thrombocytopathy in a chronic hemodialysis patient.
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A survey of alcohol-related problems and their treatment.
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Public attitudes toward increasing the price of alcoholic beverages.
Approximately half of all respondents surveyed in Ontario are satisfied with current pricing of alcoholic beverages, and approximately two-thirds of all drinkers surveyed would pay more if higher prices would help reduce the prevalence of alcoholism.
Ulcerative colitis: the experience of a Sydney teaching hospital.
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Gastric ulcer, duodenal ulcer and gastric carcinoma: a case-control study of certain social and environmental factors.
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The clinical application of oesophageal motility studies.
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Clinical, manometric, and pathological studies in diffuse oesophageal spasm.
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Gastrointestinal complications of radiotherapy.
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Computers in nursing. Spreading the word.
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Diffuse muscular spasm (diffuse muscular hypertrophy of the oesophagus).
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