Search PubMed⌕ Search

Biomedical subjects

M Gersdorff

Publications and source records attributed to M Gersdorff.

At least 91 records · Page 5Linked to original sources

[Treatment of tinnitus. What hope of recovery? What therapeutic method?].

Global therapeutic efficacy was evaluated after treatment of 100 patients with tinnitus. Characteristics of the affection were studied and different therapies applied. After a mean follow up of 4 months, marked improvement was noted in symptomatology in 33% of cases, including 8% of patients indicating total disappearance of tinnitus or its marked reduction. Efficacy of most treatments, notably medication, is open to doubt, while electrophysiological means such as percutaneous and transtympanic electrical stimulation possess specific indications. The need for basic studies of the physiopathology of tinnitus, as well as for extensive multicentre clinical trials to assess the different therapeutic methods used, is stressed.

Adult↗

[The zinc sulfate overload test in patients suffering from tinnitus associated with low serum zinc. Preliminary report].

This work studies the efficiency of the zinc overloading in the treatment of patients suffering from tinnitus with hypozincemia. The authors have positive results about 52% of cases: in 15% there was a good amelioration and in 37% there was a little but significant amelioration of their symptoms. The authors have also found on that this type treatment with zinc of overloading is more efficient in males than in females. It is also more efficient in types of tinnitus of a continuous character than in other types.

Adult↗

A comparative study of the clinical results obtained with plastipore and ceramic ossicular prostheses in otologic surgery.

We describe our experience with clinical tolerance to total and partial ossicular prostheses using ceramic and plastipore and the functional results obtained. We have found that ceramic is well tolerated (with a 4% incidence of rejection) in contrast to plastipore (which had a 19% incidence of rejection). The ceramic partial and total prostheses give satisfactory function results, and 63% and 62% of our patients, respectively, were found to have postoperative air-bone gaps of less than 20 dB, and average air-bone gap gains of 16 and 21 dB.

Biocompatible Materials↗

[Value of piracetam in the treatment of sudden idiopathic deafness. Preliminary report].

The authors report ten cases of sudden deafness treated by piracetam. In eight cases there was a complete recovery, in one case there was a partial recovery and in one it was a failure. There was observed in two cases a rise in the compound action potential of the electrocochleography measured after 30 minutes of the infusion in comparison with that performed 30 minutes before the infusion. They were impressed by the rapidity of the recovery and they did not encounter side effects.

Drug Evaluation↗

Phasor diagram: a comparative study between normal ears and otosclerotic ears.

The authors report their results from phase angle measurements by admittancemeter obtained by means of the phasor diagram, and conductance and susceptance tympanograms. The study was carried out on normal ears and otosclerotic ears. The authors noted a wide range of phase angle values and an absence of significant difference between the two populations studied.

Acoustic Impedance Tests↗

[Clinical aspects and surgical treatment of carotid body tumors].

The authors report their experience of three cases of carotid corpuscle tumors: two are bilateral and pertaining to the same family, one of them is associated with a bilateral tympano-jugular glomus. First they review the epidemiology and definitions of such tumors and then they develop the various clinical aspects and differential diagnosis of these tumors. They insist on the necessity of a CT scan examination and of an angiography. They give their experience of the preoperative embolization of the tumour vessels. They expose various aspects of the surgical technique, pointing out the interest of a large access, the need of a regular surgery and the necessary collaboration between head and neck surgeons and vascular surgeons. Finally they discuss the opportuneness to operate bilateral glomic tumors.

Adult↗

[Personal experience with a unicanal extracochlear implant in reference to rehabilitation in total bilateral deafness. Multicenter study. Preliminary report].

Our choice of a unicanal extracochlear implant is characterized by a reasonable attitude and simplicity. Simplicity and reason, because the already existing experiments show that in the field of cochlear implants there is no correlation a priori between the satisfaction of the research worker developing a complex electronic system in the laboratory and the satisfaction of the patient benefiting from such a system. Furthermore, the extracochlear implant respects and conserves the anatomical structure of the cochlea. It does not compromise future interventions. A replacement could be carried out in the future should a more perfected system be invented. The latter argument is particularly useful if a child is being considered for an implant. All patients with implants benefit from the following results: the satisfaction of hearing their own voice again, a better control of the voice (loudness and intensity), comprehension is facilitated (lip reading and noise perception), end of the sensation of isolation. The first results obtained are very encouraging. We find it most essential to continue our work in the same manner and with an inter-University working group (GRIC). The standardisation of results of the various teams involved seems to be imperative. We conclude by the following: At the present state of our knowledge, the unicanal extracochlear implant seems to be a reasonable solution and a realistic approach in the rehabilitation of total bilateral deafness.

Aged↗

[Treatment of tinnitus by electrical stimulation of the ear].

After a short historic review of the electrical stimulation in the treatment of tinnitus, the authors recall the fundamental principles of the bases of this therapy. Following the evolution of their ideas on this subject, they present the principles and methods of many different types of stimulation: (Transtympanic, sinusoidal, transcutaneus, auriculotherapy). They also discuss the results of their efficiency which ranges between 10 to 40%. The authors then reached an agreed upon opinion that the transtympanic electrical stimulation in square positive waves which ables them to obtain in nearly 60% of patients a positive effect, and in 23% a long term results is the most preferable one till now. They finally exposed a personal case in which the implantation of a permanent stimulation electrode was needed to be undergone, this is restricted to patients who suffer from unbearable tinnitus with profound deafness.

Electric Stimulation Therapy↗

[Prevention of cerebrospinal fluid fistulas in oto-neurosurgery].

The authors review the main postoperative complications of oto-neuro-surgical techniques, in particular those concerning CSF leak. They describe the various preventive measures for CSF fistulae both in general and during oto-neuro-surgical procedures. The importance of using a lumbar drainage routinely during these procedures is stressed. The technique and modalities of employment of lumbar drainage are described.

Cerebrospinal Fluid Otorrhea↗

[Variations of endotympanic pressure during anesthesia].

Variations in endotympanic pressure during general anaesthesia with a mixture of nitrogen protoxide and oxygen (66 and 34% respectively) were determined in 40 patients. Findings are of practical interest in ORL, particularly during tympanoplasty or drainage of a seromucus otitis media.

Acoustic Impedance Tests↗

[Controversy--open technic--closed technic. Critical review of the literature and our personal experience].

The authors have made a comparative study of the functional and auditory results, as well as an appreciation of the eradication of disease, in 64 patients having undergone open technic surgery for cholesteatoma (66 operations) and in 136 patients treated by closed technic (197 operations). The closed technic would appear to be the one of choice as regards the functional hearing results, most particularly in cases of absence of the stapedial crura. Concerning eradication of middle-ear disease, they believe there to be reason for a somewhat less categorical position towards the accepted fact of the semi-open technic (modified radical mastoidectomy) being strikingly safer than the closed technic. They deplore the difficulty of being unable validly to compare the published results obtained by various authors, due to the diversity of the surgical technics and a lack of uniformity in evaluating and presenting the results.

Biocompatible Materials↗