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Biomedical subjects

M Germain

Publications and source records attributed to M Germain.

At least 181 records · Page 10Linked to original sources

[A case of hepatocholangitis (author's transl)].

Inflammation localised to the hepatic duct in the region of the neck of the gallbladder is rare. Regression of the lesions after cholecystectomy authentified its purely inflammatory nature. Its interest comes from possible confusion with carcinoma of the common bile duct. A case of cholangitis with 8 years follow up illustrates these facts and permits a few comments on the pathology of the junction between the cystic duct and the hepatic duct.

Adult↗

[Sylvatic yellow fever in Africa recent advances and present approach (author's transl)].

Recent works carried out in west and central Africa resulted in numerous yellow fever virus isolations from sylvatic mosquitoes in the forest-savanna transitional zone. This virus was also obtained from monkeys, whereas studies on sequence and duration of the observed epizootics permitted a previsional approach of the yellow fever mechanisms in the same belt, the epidemiological importance of which was stressed ("emergence zone"). In the same course of research and publications, the prevalent part of the involved mosquitoes as virus-reservoirs was constantly emphasized ("reservoir-vector"). Recent investigations on transovarial transmission and yellow fever isolations from male mosquitoes caught in the field, provide decisive support to such a conception. It can explain that epizootics may be locally observed several years in succession, despite the fact that yellow fever virus circulation seems to be fundamentally of a dynamic character. Yellow fever virus was recently obtained from ticks and tick-eggs.

Africa↗

[Isolation of the Lagos-bat virus in the Central African Republic].

The second reported isolate of Lagos-bat virus has been obtained from bats Micropterus pusillus caught in 1974 in the Central African Empire, thus extending the geographic area of this virus and adding another species of vertebrate host among its reservoirs.

Animals↗

[Yellow fever in Senegal from 1976 to 1980 (author's transl)].

The isolation of a YF strain in Kedougou (eastern region) in December 1976 from Aedes gr. furcifer taylori lead to a mass vaccination campaign in Senegal. In 1977, 67 strains were isolated from different mosquitoes (essentially A. luteocephalus and A. gr. furcifer taylori). Among these strains, 3 were isolated from males and this very important phenomenon might explain the virus conservation during the dry season. In 1978, 55 strains were isolated from mosquitoes of the same species, but not from males, and five from monkeys (E. patas and C. aethiops). But no increase of morbidity or mortality was observed in humans. In December 1978, a YF outbreak occurred in the Gambia with 271 suspect cases and 63 deaths; 2 strains were isolated from A. aegypti. In 1979, the epidemic seemed to have disappeared. Up to now, one single strain has been isolated from mosquitoes. But danger remains, and 3 YF human cases with 2 deaths were observed in Sine-Saloum, among French unvaccinated tourists.

Aedes↗