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Biomedical subjects

M Gentilini

Publications and source records attributed to M Gentilini.

At least 379 records · Page 21Linked to original sources
PubMedDate not supplied

[Production of circulating interferon in human malaria].

The presence of an interferon-like activity inhibiting the cytopathic effect of vesicular stomatitis virus was studied in 216 sera from 100 patients with P. falciparum (67 cases), P. vivax (16), P. ovale (13), P. malariae (4) infections. 87% of patients were found positive on one or more occasions. The prevalence of interferon-like activity was similar in all 4 species. Titers varied between 20 to 320 U/ml and were found to be higher in Europeans experiencing a primary attack of malaria (mean = 72 U/ml) than in subjects from hyperendemic areas of West Africa (mean = 37 U/ml). In patients followed-up either a delayed positivity or an increase of interferon-like activity was found in 60% of cases. High titers were observed up to the 3rd month. The viral inhibitory activity met all criteria for defining interferon. Seroneutralization assays using anti-alpha and anti-gamma interferon antibodies showed in 5 patients that human malaria was associated with the presence of a gamma interferon.

Africa, Western↗
PubMedDate not supplied

[Clinical and diagnostic features in seven cases of sacro-iliac tuberculosis. Contribution of bone scintigraphy (author's transl)].

Sacro-iliac tuberculosis was detected in seven African immigrants following attacks of sacrolumbar pain with fever, over a period of five years. Two of the patients had a previous history of tuberculosis, and in six out of the seven cases the osteo-articular affection was part of a multifocal tuberculous disease. The value of bone scintigraphy is discussed. Surgical treatment was performed together with medical therapy in three cases.

Adult↗
PubMedDate not supplied

[Effect of the use of drinking water on the pathogenic fecal flora in a Sahel rural region].

Within the scope of a village hydraulic programme, in a Sahel rural area, an investigation was conducted in a school to determine the effect of the use of drinking water on fecal flora. One year following the installation of a hydraulic pump, it was observed that pathogenic salmonellae, shigellae and amoebic cysts had virtually disappeared. In contrast, the perennial character of viral contamination was demonstrated. Water guaranteed potable, therefore, appears to be an essential factor in the prevention of infections due to fecal pathogenic microorganisms. It is essential, however, that the areas surrounding the pumps be subjected to strict supervision to avoid pollution of the underground water sheet.

Adenoviridae↗