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Biomedical subjects

M Gavrilescu

Publications and source records attributed to M Gavrilescu.

43 records · Page 3Linked to original sources
PubMedDate not supplied

[Liquid medium for culturing Neisseria gonorrhoeae].

An original fluid medium, containing lactalbumin hydrolysate, developed for the cultivation of gonococci is described. The medium is cheap, readily prepared, efficient insuring appraisable multiplication of the microorganism, and can be stored for a long time. In the authors' experience subculture in fluid medium is preferable to other methods used for testing sensitivity to antibiotics.

Culture Media↗
PubMedDate not supplied

[Immunopathological circumstances in the structure of complications appearing after smallpox vaccination].

Investigations were carried out concerning the dynamics of antivaccinal antibodies and the structure of serum proteins in relation to the clinical manifestations following upon smallpox vaccination. In general, immunity is not apparently influenced by postvaccinal complications may be associated with immunoprotein perturbations, manifested by an increase in the alpha2-globulin fraction and, inconstantly, in the gamma-globulin fraction. Immunoelectrophoretic determinations revealed a relatively constant IgM and IgG deficiency. Postvaccinal dysglobulinemia may accompany various clinical forms, suggesting a temporary deficient immunological response. In one case of agammaglobulinemia, revaccination produced a deep vaccinal ulcer, with extensive necrosis (giant necrotic vaccinia). In order to decipher the substrate of the reaction in the clinical forms with distal manifestations or generalized vaccinia, skin biopsies were performed. The lesional vasculoallergic substrate of the skin lesions does not exclude the local aggression of the vaccinal virus, which was isolated by viral determinations.

Adolescent↗