[Gastric lipoma: a rare cause of upper digestive hemorrhage].
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Biomedical subjects
Publications and source records attributed to M Garbay.
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The authors report a series of eight primitive retro-peritoneal tumors, which were difficult to diagnose because of the late appearance of the symptoms. The intravenous urogram is the only satisfactory fundamental examination, possibly completed with ultrasound, CT scanning, and, if necessary, angiography. Extensive surgery allowed total exeresis in most cases. But histological examination remains difficult. Mesenchymomas, the most frequent, are very often malignant. Two cases of association with other malignant tumors were observed. Adjuvant procedures add little to life expectancy and total surgery is alone likely to be effective.
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Three cases of acute gangrenous acalculous cholecystitis, revealed by a postoperative septic shock, are reported. Clinical examination was negative and the surgery gave the diagnosis. Infection with biliary stasis and ischaemia accounts for this pathological entity. The very serious prognosis of this condition can only be reversed by cholecystectomy.
When confronted with the fortuitous discovery of cholelithiasis, a simultaneous operation is advisible in view of the drawbacks of performing a second operation and the risks of postoperative cholecystitis. Analysis of the author's results and those reported in the literature shows only a slightly increased morbidity rate and a similar mortality rate. In high-risk patients, and if the cholecystectomy appears difficult, the removal of the stones followed by a cholecystostomy is less aggressive and faster.
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A 60-year-old man under digitalis treatment for hypertensive heart tried to commit suicide by absorbing a 15 mg dose of digitoxin. Severe intestinal bleeding occurred 12 hours later, followed by pseudo-occlusive syndrome and ischaemia of the distal lower limbs. On abdominal incision the whole gut was found to be invaded by haemorrhagic necrosis and perforated on three points. The patients subsequently died of peritonitis. The responsibility of digitoxin in these events was demonstrated by the absence of any other cause of ischaemia, such as heart failure, shock, arrhythmia, consumption coagulopathy or use of sympathomimetic drugs. This case shows that the vasoconstrictor effect of digitalis, experimentally demonstrated but clinically controversial, is a reality, and that digitalis compounds are contra-indicated in patients with haemorrhagic necrosis of the digestive tract.
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