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Biomedical subjects

M Gajdos

Publications and source records attributed to M Gajdos.

At least 37 records · Page 2Linked to original sources

[Hemophilia from the viewpoint of the neurosurgeon].

The authors describe a case of cerebral haemorrhage associated with haemophilia A--their own observation, findings and confrontation with data in the literature. They draw attention to the rare incidence of the above complication, discuss the site of haemorrhage and possibilities of treatment.

Adult↗

[Pefloxacin in the treatment of recurrent urinary tract infections].

Thirty-seven patients with relapsing infections of the urinary tract were treated with pefloxacine, 400 mg/12 h for a period of 7-28 days. The clinical success of treatment was 100%, the bacteriological success 95%. Within 3-4 weeks after termination of treatment 63% of the patients did not develop a relapse, in particular those who did not have morphological changes of the kidneys. Side-effects-gastrointestinal, nervous, dermatological--during treatment were not severe. The results are comparable with results of the effect of ofloxacine in a similar group of patients.

Adult↗

[Pharmacokinetic modeling in clinical practice: pefloxacin].

Pharmacokinetic modelling allows to set up a therapeutic plan for administering a drug. The advances of this procedure are particularly remarkable in drugs discharged by the liver. The principles of this approach are presented and illustrated on the treatment with pefloxacin. The potential causes of the adverse effect of the drug observed in one patient of the series studied could thus be suggested.

Computer Simulation↗

Erythrocyte transport of middle molecular substances.

Middle molecule (MM) fractions were isolated from the erythrocytes of patients in chronic renal failure on conservative treatment, and healthy subjects and fractionated on Sephadex G 15. Most MM fractions were found in markedly higher concentrations in erythrocytes than in plasma. A model inhibitor of gluconeogenesis found previously in plasma and urine of the uraemic subjects was found also in the erythrocytes. Repeated washing of the erythrocytes with isotonic solution of NaCl did not wash out the inhibitor of gluconeogenesis from erythrocytes.

Erythrocytes↗