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Biomedical subjects

M Gabr

Publications and source records attributed to M Gabr.

At least 19 recordsLinked to original sources
PubMed1998

Organ transplantation in developing countries.

Organ transplantation has become an effective means of restoring health and saving lives, but a number of difficulties remain to be overcome. Especially in developing countries, greater clarity is needed on the sociocultural, economic, ethical, legal and technical factors involved.

Developing Countries↗
PubMed1995

Health professions development.

Health professions development is an integral part of national health plans. It is influenced by various factors and should be continuously updated to meet the changing health situation and related disciplines of the country. There are three forms of establishing a health manpower development plan: a market-oriented form, a goal-achievement form and a normative form. A combination of all forms is best if carried out by a community-oriented team of academic health professions and health care providers. Although countries of the Eastern Mediterranean Region share many demographic, geographic, and sociocultural characteristics, there are marked differences in resources, health manpower structure and availability in health services. Health professional development plans should be formulated according to existing situations. Other factors influencing health manpower development in the future include political, social and economic trends, changes in morality and disease patterns, industrialization, availability of health services and academic institutions. Perspectives guiding planning for the development of various categories of health professionals are presented.

Delivery of Health Care↗
PubMed1989

Speech manifestations in lateralization of temporal lobe seizures.

To evaluate the role of speech manifestations in lateralization of temporal lobe seizures, we reviewed videotapes of 100 complex partial seizures in 35 patients who underwent temporal lobectomy for intractable epilepsy. All patients had prolonged electroencephalographic video monitoring with scalp and subdural electrodes, and their speech dominance was determined with an intracarotid amobarbital test. Speech manifestations were observed in 79 seizures and were classified as vocalization, normal speech, or abnormal speech. Vocalization of sounds without speech quality occurred ictally in 48.5% of patients. Normal speech (identifiable speech) occurred ictally in 34.2% of patients. Abnormal speech (speech arrest, dysphasia, dysarthria, and nonidentifiable speech) occurred in 51.4% of patients, either ictally or postictally. Of all the above speech manifestations, only postictal dysphasia and ictal identifiable speech had significant lateralizing value: 92% of patients with postictal dysphasia had their seizures originating from the dominant temporal lobe (p less than 0.001), and 83% of those with ictal identifiable speech had their seizures from the nondominant side (p = 0.013). This study shows that speech manifestations are common in complex partial seizures of temporal lobe origin and can provide an excellent clinical tool for lateralization of seizure onset.

Adolescent↗
PubMed1983

Endocrine profiles in pediatric andrology. I. Thyroid-stimulating hormone response to thyrotropin-releasing hormone in normal and protein-calorie malnourished infants.

Thryotropin-releasing hormone (TRH) was intravenously administered to eight normal control infants and ten infants with kwashiorkor. Stimulation caused by TRH was measured at various time intervals. The basal total protein mean value +/- SE was 6.9 +/- 0.3 and 4.0 +/- 0.3 g/dl for the control and kwashiorkor groups, respectively. Serum total thyroxine was 7.7 +/- 0.6 and 4.8 +/- 0.8 micrograms/dl for the control and kwashiorkor groups, respectively. Serum levels of thyroid-stimulating hormone (TSH) were 3.2, 13.5, 9.0, 7.4, and 8.0 microU/ml for the controls before stimulation and 20, 60, 90, and 120 min after stimulation, respectively. The corresponding values for the infants with kwashiorkor were 5.7, 13.9, 14.9, 15.2, and 15.3 microU/ml, respectively. The delayed TSH response to TRH stimulation in the infants with kwashiorkor was attributed to disturbance in the hypothalamic-pituitary-thyroid axis.

Female↗
PubMed1979

Synthesis of 4-substituted aminobenzoate quaternary salts as potent antispasmodic agents.

N-(Diethylaminoethyl)-4-substituted aminobenzoate quaternary salts, N-(diethylaminoethyl)-4-substituted aminobenzamide quaternary salts, 4-substituted acylaminobenzamide quaternary salts, and 4-substituted acylaminosalicylamide derivatives were prepared and tested for antispasmodic activity. Preliminary pharmacological tests on isolated guinea pig ileum revealed that the new compounds possess nonspecific inhibitory action on smooth muscles.

Aminobenzoates↗
PubMed1977

Lactose tolerance in normal Egyptian infants and children and in protein calorie malnutrition.

Oral lactose tolerance test was performed on a total of 100 cases of normal Egyptian infants and children aged 6 months to 12 years. The same test was performed on 30 cases of protein calorie malnutrition (15 cases of marasmus and 15 cases of kwashiorkor). Detection of sugar and determination of pH were also carried out on all stools passed after the test. Lactose intolerance, as judged by a maximal blood glucose rise of 20 mg. or less and/or stools positive for sugar with a pH less than 6 following lactose ingestion, was observed as follows in normal cases: 12% in the age group 6 months to 2 years, 32% in the age group 2 to 5 years, 32% in the age group 5 to 9 years, and 80% in the age group 9 to 12 years. On the other hand, lactose intolerance was demonstrated in 73.3% of cases suffering from protein malnutrition. The aetiology and practical implications of the present findings of lactose intolerance on normal and malnourished children are discussed.

Child↗