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Biomedical subjects

M G Wise

Publications and source records attributed to M G Wise.

30 records · Page 2Linked to original sources

Causes of organic mood disorder.

A retrospective review of the records of 755 patients seen by a psychiatric consultation-liaison service in a general hospital was performed. The authors found that 87% of manic patients and 38% of depressed patients had a diagnosis of organic mood disorder. The most frequent precipitants of mania were corticosteroids, human immunodeficiency virus (HIV) infection, and temporolimbic epilepsy. The most frequent precipitants of depression were stroke, Parkinson's disease, and HIV infection.

Bipolar Disorder↗

Cerebrospinal fluid abnormalities in patients without AIDS who are seropositive for the human immunodeficiency virus.

Lumbar punctures were done on 114 consecutive active duty patients referred for evaluation of positive tests for antibodies to the human immunodeficiency virus (HIV). Eighty-eight percent of these patients appeared to have early HIV infections, as evidenced by intact delayed hypersensitivity, T helper lymphocyte counts greater than 400/mm3, and lack of constitutional symptoms. Forty-four (38.6%) of the patients met our criteria for abnormal cerebrospinal fluid (CSF); another 13 (11.4%) had borderline elevations of nucleated cells or protein and could not be definitely classified as having normal or abnormal CSF. No significant differences existed between the patients with normal and abnormal CSF with regard to age; sex; race; serum FTA-Abs; clinical staging; absolute T helper lymphocyte counts; or cytomegalovirus, Toxoplasma, or Epstein-Barr virus serologies. Seventy-two percent of the patients with abnormal CSF had evidence of possible viral infection of the central nervous system (CNS), as evidenced by increased CSF IgG, increased IgG synthesis rates, or the presence of oligoclonal bands. We found that a significant percentage of asymptomatic patients with apparent early HIV infections have abnormal CSF that is possibly due to CNS involvement by HIV.

Central Nervous System Diseases↗

Predictors of successful alcohol rehabilitation in an Air Force population.

In order to find predictors of success in alcohol treatment, the authors conducted a 1-year follow-up of 71 active duty military personnel treated in a 28-day inpatient program. Success at 1 year follow-up was then compared with variables collected on a patient questionnaire completed at the beginning of rehabilitation. A family history of emotional disorders, together with a single incident precipitating treatment, was associated with a positive alcohol rehabilitation outcome.

Aerospace Medicine↗

Working with medicated clients: a primer for social workers.

The vastly increased use of prescribed and nonprescribed drugs in this society means that even such traditional social work activities as assessment and advocacy now frequently require a knowledge of the effects of drugs. Integrating a knowledge of basic concepts of pharmacology into practice will enable the social worker to help clients more effectively and to improve the health care they receive.

Adult↗

Three cases of AIDS-related psychiatric disorders.

Psychiatric disorders related to acquired immune deficiency syndrome (AIDS) can take various and complex forms. The authors present cases of AIDS patients in whom paranoia, organic brain syndrome, depression, or suicidal ideation was present.

Acquired Immunodeficiency Syndrome↗

Case report of ECT during high-risk pregnancy.

The authors present the case of a depressed woman given ECT during pregnancy and list administrative and monitoring techniques for protection of both fetus and mother when ECT is administered during pregnancy.

Adult↗

The clinical and financial burden of mood disorders. Cost and outcome.

Depressive disorders are a chronic, recurrent, and severe burden to both patients and their families. Depressive disorders represent a major national public health problem, ranking within the top 10 most costly diseases in the United States. In 1990, depressive disorders afflicted at least 11 million Americans and cost the U.S. economy an estimated $44 billion. In addition, affective disorders are associated with increased accident rates, increased rates of substance abuse (especially alcoholism), increased medical hospitalization, and an increase in somatic illnesses and outpatient medical utilization. Despite their ranking as a major health problem, depressive disorders are often underdiagnosed and undertreated. Brief treatment strategies that focus only on acute episodes are often ineffective and result in chronic impairment, impairing performance at work and socially. Inadequate treatment increases costs, suffering, and lost productivity. Recent data suggest that effective treatment of depression requires long-term, skillful follow-up and active pharmacotherapy.

Cost of Illness↗