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Biomedical subjects

M G Koppikar

Publications and source records attributed to M G Koppikar.

7 recordsLinked to original sources

Ectopic human placental lactogen and beta-human chorionic gonadotropin in gastric fluid of patients with malignant and non-malignant conditions of the stomach.

Human placental lactogen (hPL) and beta-human chorionic gonadotropin (beta-hCG) in gastric aspirates and sera of 24 patients with malignant (12 patients) and non-malignant (12 patients) conditions of the stomach were studied. In patients with cancer of the stomach, hPL and beta-hCG were found to be present in gastric aspirate at higher frequency than in serum. The concentration of these hormones in gastric aspirate was higher than in serum. In 2 patients with duodenal ulcer beta-hCG was found to be present in gastric aspirate, 1 of them having the hormone in circulation as well, while none of the 12 patients with non-malignant conditions of the stomach showed presence of hPL in their gastric aspirate or serum.

Adult↗

Wandering spleen.

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Diagnosis, Differential↗

Management of pain after abdominal surgery: dipyrone compared with pethidine.

1 Dipyrone 2.5 g was compared with pethidine 100 mg in a double-blind parallel group study. 2 Patients with moderate or severe postoperative pain following abdominal surgery received one of the two drugs intramuscularly. 3 The two treatment groups were homogeneous when analyzed by age, weight, height, sex, and initial severity of pain. 4 The onset degree and duration of pain relief afforded by both drugs was similar when the groups were compared as a whole or according to initial pain level. 5 No side-effects were attributed to either drug in this study.

Abdomen↗

A double-blind comparison of parenteral dipyrone and pethidine in the treatment of post-operative pain.

A double-blind trial was carried out in 100 patients with moderate to severe post-operative pain to compare the analgesic effectiveness over a 6-hour period of single intramuscular injections of 2.5 g dipyrone and 100 mg pethidine. Maximum pain relief was seen 2 hours after drug administration in both groups and there was no statistically significant difference in responses. No side-effects were reported.

Adult↗