Rapid detection of bacteraemia.
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Biomedical subjects
Publications and source records attributed to M G Keaney.
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A total of 102 patients with urinary tract infection were treated with 400 mg norfloxacin twice daily for three days. Midstream specimens of urine were cultured at the initial visit and also one and five weeks after treatment. Forty-eight out of 50 patients (96%) with significant bacteriuria were successfully treated and remained free from recurrences during the follow-up period. There was no evidence of serious toxicity and only minor adverse symptoms were recorded.
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Thirty one of 60 consecutive isolates of Streptococcus faecalis produced a reaction in both D and G streptococcal grouping sera. A close correlation was found between this grouping reaction and haemolysin production, resistance to erythromycin, tetracycline, and trimethoprim, and delayed fermentation of sorbitol.
On examination of Bactec blood cultures for pneumococcal antigen by countercurrent immunoelectrophoresis the consistent presence of a non-specific protein band caused problems with the interpretation of results, even in laboratories experienced in performing countercurrent immunoelectrophoresis. When the Bactec blood culture system is used, countercurrent immunoelectrophoresis should not be relied on for the detection of pneumococcal antigen.