Criteria for the selection of rectal cancers for local treatment: a clinicopathologic study of low rectal tumors.
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Adenocarcinoma↗
Biomedical subjects
M G Greaney
Publications and source records attributed to M G Greaney.
Effect of cigarette smoking on the lower oesophageal sphincter.
Observations on the effect of smoking on lower oesophageal sphincter pressure (LOSP) are based on station pull-through techniques of eosophageal manometry and recent studies have suggested that these techniques are inaccurate. Reproducible measurements of LOSP may be achieved with a rapid pull-through (RPT) method of manometry. This method was used to determine the effect of cigarette smoking on LOSP in 10 asymptomatic volunteers and in a group of 10 patients with symptoms of gastro-oesophageal reflux. Basal LOSP measurements in the two groups were not significantly different but LOSP was reduced by 19% in asymptomatic subjects (p less than 0-01) and by 21% in symptomatic patients (p less than 0-02) during cigarette smoking. The results suggest that smoking should be avoided in the clinical management of gastro-oesophageal reflux.
Adolescent↗
Duration of symptoms and prognosis of carcinoma of the colon and rectum.
The symptomatic history in 335 instances of carcinoma of the colon and rectum was compared with the long term survival of the patients. The patients were divided into four groups according to the duration of symptoms recorded on admission to the hospital. There was a significantly higher incidence of resections for cure in those who had symptoms for less than five months' duration, but the long term survival of patients was not significantly related to the duration of symptoms. The pathologic findings suggested that patients presenting early had more virulent or biologically active tumors, and the onset of symptoms in these patients more frequently included complaints of abdominal pain and multiple symptoms. It appears that the prognosis of carcinoma of the colon and rectum is largely determined by the biologic behavior of the primary tumor rather than by the length of the symptomatic illness, and it also appears that the earlier diagnosis of symptomatic patients may result in comparatively small gains in the survival rate.
Colonic Neoplasms↗
Torsion of the testis: a review of 22 cases. Improved diagnosis and earlier correction.
Greater awareness of the possibility of torsion of the testis and earlier exploration has led to the saving of 14 out of 19 acutely twisted testicles.
Adolescent↗