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Biomedical subjects

M G Grand

Publications and source records attributed to M G Grand.

At least 55 records · Page 3Linked to original sources
PubMed1986

Limited retinal detachment. A retrospective analysis of treatment with transconjunctival retinocryopexy.

Two hundred forty-one eyes with a "limited retinal detachment" were treated between 1967 and 1983 by transconjunctival retinocryopexy without scleral buckling. Follow-up ranged from 6 months to 10 years (mean, of 34 months). Anatomic reattachment was accomplished with retinocryopexy alone in 95% (228 eyes) of cases. Thirteen eyes (5%) were anatomic failures, but 12 of these were subsequently reattached with additional surgery. Risk factors for anatomic failure included multiple breaks, vitreous hemorrhage, and breaks with a rolled posterior edge. Visual results indicated that 229 eyes (95%) had stable or improved vision, while 12 eyes (5%) lost two or more Snellen lines. Causes for visual deterioration included premacular fibroplasia, proliferative vitreoretinopathy, and preexisting ocular pathology. Single breaks occurred in 172 eyes (71.4%), and multiple breaks in 69 eyes (28.6%). Associated clinical findings included high myopia (17%), surgical aphakia (12%), and retinal detachment in the fellow eye (27%).

Conjunctiva↗
PubMed1985

Vitrectomy without scleral buckling for primary rhegmatogenous retinal detachment.

Trans pars plana vitrectomy with air-fluid exchange was performed on 29 selected cases of primary rhegmatogenous retinal detachment in which scleral buckling would be the usual surgical approach. The group contained 20 phakic eyes, two aphakic eyes, and seven pseudophakic eyes; the macula was detached preoperatively in 17 eyes (66%). The reattachment rate after one operation was 79% (23 of 29 eyes); after two operations this increased to 93% (27 of 29 eyes). Visual acuities of 20/50 or better were achieved in 22 of 27 successfully treated cases (81%). Vitrectomy without scleral buckling may allow retinal reattachment with excellent visual results in selected cases of primary rhegmatogenous retinal detachment.

Adolescent↗
PubMed1984

Preoperative antibiotic soaking of silicone sponges. Does it make a difference?

A prospective randomized trial was carried out during the years 1974 to 1981 to determine whether preoperative antibiotic soaking of silicone sponges used in retinal detachment surgery would reduce the incidence of postoperative infection and extrusion. During this period 2972 consecutive primary scleral buckles were performed and in 921 (31%) of the cases an episcleral sponge was utilized either alone or in conjunction with a hard silicone encircling band. In alternate cases the sponge was soaked in an antibiotic solution for at least 30 minutes prior to insertion. In the remaining cases the sponge was not soaked. Overall, a statistically significant (P = 0.00018) seven-fold reduction in the rate of infection or extrusion was observed in cases where the silicone sponge was soaked preoperatively in antibiotics. An additional result of the study showed the rate of sponge removal was significantly increased by the use of multiple episcleral sponges (P = 0.00002).

Anti-Bacterial Agents↗
PubMed1984

Xenon arc photocoagulation of proliferative diabetic retinopathy. A review of 2688 consecutive eyes in the format of the Diabetic Retinopathy Study.

In a retrospective study, 2688 eyes treated with xenon arc photocoagulation which would have qualified for inclusion in the Diabetic Retinopathy Study (DRS) were reviewed in the format of the DRS. When comparable risk groups were compared, the results of treatment were even more favorable than reported in the DRS without the severe complications attributed to xenon treatment in the DRS. A critical analysis of the DRS gives clues for the greater amount of visual loss found with xenon than argon in the DRS. Since these complications may be avoidable in some cases, and since xenon has been shown to be at least as effective as argon, it should continue to be used in the treatment of proliferative diabetic retinopathy.

Argon↗
PubMed1984

Exogenous Aspergillus endophthalmitis.

A 49-year-old man developed Aspergillus endophthalmitis after a perforating corneal injury. The infection was successfully treated with antifungal therapy and surgery.

Amphotericin B↗
PubMed1983

Xenon arc photocoagulation of proliferative diabetic retinopathy (a review of 2688 consecutive eyes in the format of the diabetic retinopathy study--DRS).

Over 2500 xenon arc-treated eyes which would have qualified for inclusion in the DRS were reviewed in the format of the DRS. When comparable risk groups were compared, the results of treatment were even more favorable than reported in the DRS without the severe complications attributed to xenon treatment in the DRS. A critical analysis of the DRS gives clues for the greater amount of visual loss found with xenon than argon in the DRS. Since these complications may be avoidable in some cases and since xenon has been shown to be at least as effective as argon, it should continue to be used in the treatment of PDR.

Argon↗
PubMed1981

Computerized axial tomography in the detection of intraocular foreign bodies.

CAT scanning was used in the localization of intraocular and periorbital foreign bodies in 36 consecutive patients. The method was found to be convenient, well-tolerated by the patient, and provided accurate and useful clinical information. Six cases are described to illustrate clinical situations where traditional localizing methods were unable to supply satisfactory information and where CAT scanning proved to be of significant assistance. This included uncooperative patients, multiple foreign bodies, anterior foreign bodies, and foreign bodies adjacent to the posterior scleral wall.

Adult↗
PubMed1981

Treatment of blood-induced glaucoma by trans pars plana vitrectomy.

Three patients are described who presented with blood-induced glaucoma. The cause of the vitreous hemorrhage was different for each patient, and included branch vein occlusion, diabetic retinopathy, and cataract extraction. The clinical findings common to all three cases consisted of degenerated red blood cells in the anterior chamber and vitreous cavity, a broken anterior vitreous face, open angles, and the absence of rubeosis iridis. Pars plana vitrectomy and anterior chamber irrigation resulted in normalization of intraocular pressure in each patient.

Aged↗
PubMed1981

Panfunduscope contact lens for argon laser therapy.

The Rodenstock panfunduscope lens adds significantly to the safety of argon laser pan retinal ablation by allowing easy and constant visualization of the relationship of burns to the fovea. One can constantly monitor the overall pattern of photocoagulation being achieved, thereby eliminating skipped areas. The increased safety and speed of the procedure may benefit both surgeon and patient.

Argon↗
PubMed1981

Polytetrafluoroethylene in experimental retinal detachment surgery.

Expanded polytetrafluoroethylene (PTFE) material was evaluated as an adjunctive material for retinal detachment surgery. A 4 mm sponge was wrapped in a 4 mm diameter tube of PTFE and sutured episclerally. Additionally, PTFE was rolled and sutured into an episcleral pocket as an implant material. Microscopic sectioning demonstrated a minimal inflammatory response and ingrowth of connective tissue into the PTFE. The intrascleral PTFE had also become successfully infiltrated with connective tissue, creating a thick, fibrovascular intrascleral implant. This material may prove useful in preventing extrusion of Silastic sponge exoplants, as a buckling element for intrascleral procedures, or as a covering for staphylomatous areas that require episcleral buckling.

Animals↗
PubMed1980

Technique for removing a fishhook from the posterior segment of the eye.

A man was admitted to the hospital with a penetrating injury to the eye caused by a fishhook. One of the current techniques for removing cutaneously embedded hooks was used to remove it. This technique, in conjunction with detachment surgery, resulted in the successful restoration of vision in our patient. To our knowledge, this is the first report of the successful removal of a fishhook that penetrated the retina and lay within the vitreous of the eye.

Eye Foreign Bodies↗
PubMed1980

Subretinal lesions following scleral buckling procedure.

In five patients, subretinal lesions developed several weeks after scleral buckling procedures for retinal detachment. The lesions appear to be subretinal, well circumscribed, dome shaped, yellow-orange unassociated with edema or disturbance of the overlying retina, and unaccompanied by overlying inflammatory cells in the vitreous. All were located temporal to the fovea in the posterior pole. The angiographic pattern was characteristic, showing obscuration of the usual appearance of the lamina choroidocapillaris. Throughout the angiogram, the lesion remained unchanged, showing no increasing hyperfluorescence or hypofluorescence. Final visual acuities were 20/40 or better in all five patients, with follow-up periods from three to seven months. There is some evidence to suggest that these lesions represent persistent, isolated pockets of subretinal fluid.

Adult↗
PubMed1980

Incidence of cystoid macular edema following scleral buckling procedure.

Sixty eyes of 58 patients who underwent scleral buckling procedures were prospectively evaluated with postoperative fluorescein angiograms. Forty-three percent of these eyes showed angiographic cystoid macular edema (CME). Aphakic patients showed a 64% incidence of cystect the final visual acuity of aphakic patients but significantly reduced the visual recovery in the phakic group. The incidence of CME was not related to preoperative foveal detachment, duration of aphakia, duration of detachment, surgical approach, or refraction.

Aphakia↗
PubMed1980

Electrocoaptation conjunctival closure in retinal detachment surgery.

This report describes the method of electrocoaptation, a sutureless technique for closure of the conjunctiva, in 75 patients who underwent primary scleral buckling or vitrectomy procedures. The technique is safe, rapid, easily performed, and results in a secure wound that heals well.

Conjunctiva↗
PubMed1980

A flute syringe for vitreous surgery.

We have devised a method whereby an inexpensive, disposable tuberculin syringe may be used as a flute syringe with retrograde flushing capability. This syringe is particularly useful in vitreous surgery and alleviates problems that occur with commercially available instruments of this type.

Humans↗
PubMed1979

Sudden monocular visual loss in pseudotumor cerebri.

We describe a patient with papilledema due to benign intracranial hypertension who had sudden, painless monocular visual loss. Fear of further visual deterioration prompted vigorous therapeutic efforts to reduce intracranial pressure. Subsequent neuro-ophthalmologic evaluation disclosed that the visual loss was due to a subretinal neovascular membrane. Vision continued to improve after medical therapy was discontinued, and was accompanied by complete resolution of papilledema and headache. In any patient with minimal papilledema, sudden visual deterioration should initiate a search for other causes rather than zealous therapeutic efforts to reduce intracranial pressure.

Blindness↗
PubMed1979

Retinal complications of gas myelography.

Bilateral retinal and preretinal hemorrhages with an acute and permanent partial loss of visual acuity developed in a 60-year-old man after an oxygen myelogram. In order to increase the contrast of the myelogram, a greater volume of oxygen was injected in the subarachnoid space than the volume of CSF that was removed. It is believed that the hemorrhages and visual loss were secondary to the sudden increase in CSF pressure caused by the excess volume of oxygen injected.

Humans↗